Element:Mabel

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Description

Mabel is a LTR retrotransposon found in the genome of the nematode parasite Brugia malayi (Llorens et al. 2009). Its name is an acronym derived from "Brugia malayi Bel/Pao element". Mabel belongs to the Tas clade (Copeland et al. 2005) within Branch 1 of the Bel/Pao family (Llorens et al. 2009). The genome of Mabel is 5.4 Kb in size (5436 bp long) and presents a single long polyprotein of 1811 amino acids containing both gag and pol associated domains (Llorens et al. 2009). No LTRs have been yet identified for this element.

Structure

Mabel.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession: 170588120
Clade: Tas
Cluster or genus: Undetermined
Branch or class: Branch 1
Family: Bel/Pao
System: LTR retroelements
Host:
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Brugia malayi.gif
Brugia malayi
Cortesy of CDC-DPDx
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Welcome to the Gypsy Database (GyDB) an open editable database about the evolutionary relationship of viruses, mobile genetic elements (MGEs) and the genomic repeats where we invite all authors to contribute with their knowledge to improve and expand the topics.
Cite this project:

Llorens, C., Futami, R., Covelli, L., Dominguez-Escriba, L., Viu, J.M., Tamarit, D., Aguilar-Rodriguez, J. Vicente-Ripolles, M., Fuster, G., Bernet, G.P., Maumus, F., Munoz-Pomer, A., Sempere, J.M., LaTorre, A., Moya, A. (2011) The Gypsy Database (GyDB) of Mobile Genetic Elements: Release 2.0 Nucleic Acids Research (NARESE) 39 (suppl 1): D70-D74 doi: 10.1093/nar/gkq1061

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