Description
Mabel is a LTR retrotransposon found in the genome of the nematode parasite Brugia malayi (Llorens et al. 2009). Its name is an acronym derived from "Brugia malayi Bel/Pao element". Mabel belongs to the Tas clade (Copeland et al. 2005) within Branch 1 of the Bel/Pao family (Llorens et al. 2009).
The genome of Mabel is 5.4 Kb in size (5436 bp long) and presents a single long polyprotein of 1811 amino acids containing both gag and pol associated domains (Llorens et al. 2009). No LTRs have been yet identified for this element.
Structure
Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:
| MA=matrix
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PR=protease
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DU or DUT=dUTPase
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TM=transmembrane
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TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
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| CA=capsid
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RT=reverse transcriptase
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INT=Integrase
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CHR=chromodomain
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| NC=nucleocapsid
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RH=RNaseH
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SU=surface
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MOV=movement protein
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| PPT=polypurine tract
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PBS=primer binding site
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ATF=aphid transmission factor
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VAP=virion associated protein
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Related literature
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