Element:BAEVM

Description Baboon Endogenous Virus (BaEVM) is a C-type endogenous retrovirus that occurs in Old World apes. BAEVM was originally isolated in mandrill cellular cultures (Beneviste et al. 1974; Todaro et al. 1974) and is detectable in placental tissue (Todaro, Sherr and Beneviste 1976). The genome of BaEVM strain M7 is taken as a representative. The genomic structure of this retrovirus is 8.5 Kb size including LTRs of 0.55 Kb, its internal region displays a Primer Binding Site (PBS) complementary to a tRNAPro, three Open Reading Frames (ORFs) for gag, pol and env genes characteristic of retroviruses; and a Polypurine Tract (PPT) adjacent to the 3′LTR ( Kato et al. 1987). Structure Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean: MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein Related literature Retroviruses. (Coffin, Hugges and Varmus 1997)

Genbank accession: D10032 Clade: Undetermined Cluster or genus: Gammaretrovirus Branch or class: Class 1 Family: Retroviridae System: LTR retroelements Host: Explore the Tree Life Project Mandrill sp. Image, Joaquin Panadero, Copyright, GyDB, Biotech Vana Browse all elements