Element:STcLV2PP1664

Description Simian T-Lymphotropic Virus (STcLV2PP1664) is a complex retrovirus isolated from the wild-caught bonobo (Van Brussel et al. 1998). STcLV2PP1664 is closely related to HTLV-2 retroviruses and its genomic structure is 8.9 Kb in size including LTRs of 712 nt. The internal region of this retrovirus displays a Primer Binding Site (PBS) complementary to a tRNAPro, Open Reading Frames (ORFs) for gag, pol and env genes characteristic of retroviruses, and also, accessory genes rex and tax (both essential for viral replication and cellular transformation in infected cells), and two ORFs that encode for proteins Tof and Rof (see accessory genes), STcLV2PP1664 also displays an ORF V and the Polypurine Tract (PPT) common to all retroviruses (Van Brussel et al. 1998) Structure Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean: MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein Related literature Retroviruses. (Coffin, Hugges and Varmus 1997)

Genbank accession: Y14570 Clade: Oncovirinae C-type Cluster or genus: Deltaretrovirus Branch or class: Class 2 Family: Retroviridae System: LTR retroelements Host: Explore the Tree Life Project Pan paniscus Image, courtesy of Alan Hill, Hopwood Hall College by way of the Web ZipCodeZoo project Browse all elements