Description
17.6 is a retrovirus characterized in Drosophila melanogaster (Saigo et al. 1984). 17.6 belongs to the genus Errantiviridae (Boeke et al. 1999; Pringle 1998; 1999; Hull 1999), a lineage of fly-retroviruses and LTR retrotransposons phylogenetically related to 412/mdg1 clade (Tubio, Naveira and Costas 2005). The genomic structure of 17.6 is 7.4 Kb in size including LTRs of 0.5 Kb, both LTRs present sequences for hogness box promoters. The internal region displays a Primer Binding Site (PBS) complementary to a tRNASer, three Open Reading Frames (ORFs) for gag, pol, and env genes, and a Polypurine Tract (PPT) adjacent to the 3´LTR (Saigo et al. 1984).
Structure
Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:
| MA=matrix
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PR=protease
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DU or DUT=dUTPase
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TM=transmembrane
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TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
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| CA=capsid
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RT=reverse transcriptase
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INT=Integrase
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CHR=chromodomain
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| NC=nucleocapsid
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RH=RNaseH
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SU=surface
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MOV=movement protein
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| PPT=polypurine tract
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PBS=primer binding site
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ATF=aphid transmission factor
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VAP=virion associated protein
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Related literature
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