CAARD Alignment:Ty1 Copia
Description
There are two methods of ancestral reconstruction - Joint and Marginal. In this section, we provide a multiple alignment including both input peptidases and ancestral ML sequences reconstructed using the Joint method.The alignment is available in several formats clicking below the option "Set 1". To build HMM profiles and MRC sequences we removed non-informative amino acid stretches and gaps from several ancestral ML reconstruction analyses You can also retrieve the processed Jrof output, clicking below the option "Set 2". Note however that should you cannot select option 2 is because the output was not processed.
Comments
Alignment obtained using CLUSTAL X (Thompson et al. 1997) and GENEDOC editor (Nicholas and Nicholas 1997) for manual refinement.
Groups of similarity
1= [E,Q] Glutamate and Glutamine. 2= [D,N] Aspartate and Asparagine. 3= [G,P] Amino acids frequent in β-turns 4= [S,T] Small nucleophile amino acids. 5= [K,R,H] Basic amino acids 6= [F,Y,W] Aromatic amino acids 7= [Q,E,D,N] Acidic amino acids and relatives 8= [L,I,V,M,A] Aliphatic amino acids 9= [L,I,V,M,G,P,A,F,Y,W] Hydrophobic and aliphatic amino acids
Shaded
* 20 * 40 * 60
TNP2 : LDTGTTNHMSGSR-AAFVKLDTA-VLG-----TVRF-GDDPVARIEGHGTVVVCKN-GKL--RSF : 54
Opie-2 : VDSGCSRHMTGEA-KWFTSLTR--ASSDE---TITF-GDASSGRVMAKGTIKVNDK------FML : 52
Endovir : FDSGASRHMTGSQ-ANLNNYSS--VKES----NVMF-GGGAKGRIKGKGDLTETEK------PHL : 51
ToRTL1 : MDSGCSKHMIGDV-KNFLSLKT--LQGG----GVSF-GDGKNGYILGVGKV------G----RSL : 47
Sire-1 : LDSGCSRHMTGVK-EFLVNIE---PCSTS---YVTF-GDGSKGKITGMGKL-VHD--G------- : 47
Ty1 : LDSGASRTLIRSA-HHIHSASSN-P-D-----INVVDAQKRNIPINAIGDLQFHF--QDN-TKTS : 54
Ty2 : IDSGASQTLVRSA-HYLHHAT---PNSEI---NIVD-AQKQDIPINAIGNLHFNF--GTK--TSI : 53
Osser : LDSGAIYHVTPDA-RSLRDYK---PCDPI---PLKC-GGGEVHYAVGYGDLTYSFHIGPV-VIKI : 56
Bare1 : LTSGLVMNLNNCYLVPALSMNI--ISGS----CL-L-RDGYSFKSENNG--------CS---ISM : 46
Tnt1 : VDTAASHHATPVR-DLFCRY----VAGDFG--TVKM-GNTSYSKIAGIGDIITNV--GCT--LVL : 53
Ta1-3 : LDSGCTSHMSARR-DWFCSFR---EDGGPT--IL-L-GDDHSVKSQGQGSI-IETHGGTI--IGL : 54
Tto1 : IDSGATIHATPRR-ELFSSY----TLGDFG--RVKM-GNANFSTVVGKGDV-LETMNGMK--LLL : 54
Evelknieve : LDSGATHHLTSDL-NNLALHQP--YNGGE---EVTI-ADGSGLPISHSGSALLPTP-TRS--LDL : 55
Hopscotch : TDTGATDHITGDL-DRLTMHDK--YTGTD---QIIA-ANGTGMTISNIGNAIVPTS-SRS--LHL : 55
Sto-4 : IDSSATVHVANSL-QGLRTSQRL-PKGRR---TIRV-ANGVEAAVEAIGDIHLKLVNGFV--LLL : 57
Retrofit : IDTGATDHITGEL-EKLTTKEK--YNGGE---QIHT-ASGAGMDISHIGHTIVHTP-SRN--IHL : 55
MelmothAra : IDSGATHHVSHDR-SLFSS-----LDTSVLS-AVNL-PTGPTVKISGVGTLKLND--D----ILL : 51
Melmothbra : IDSGATHHVCHDR-SMYTS-----IDITTTS-NVNL-PNGMIVKISGVGIVQLNE--H----ITL : 51
Rire1 : MDSGATVHICADR-SMFSS-----FQGFNSA-PVLM-GNGVPAAVRGTGQVYLKLTSGKT--LVL : 55
Fourf : MDSGANIHVCADA-SMFTS-----YQVGRS--GALLMGNGSRAHVLGVGTVILKFTSGKT--VPL : 55
1731 : LDSGATSHMCCDR-SVFTE-----FEEHTE--KISLAGNG-FLLAKGIGTVKLKTD-LCT--LVL : 53
Ty5 : FDTGCTSHMCHDR-SMFSS-----FTRSSKKDFVRG-VGG-SIPIMGSGTV--NI--GT---VQL : 50
Copia : LDSGASDHLINDE-SLYTDSVELVPPL-----KIAVAKQGEFIYATKRGIVRLRN--DHE--ITL : 55
Yokozuna : IDSGASQNLVID--SYEKYMSNIEYLETKT--KIYV-ANGQYLFSSKKGILNVKY---NN-LPIK : 56
Ty4 : IDTGSGVNITNDK-TLLHNYED--SNRSTR--FFGI-GKNSSVSVKGYGYIKIKN--GHNNTDNK : 57
Lusen : LDSGSPYHLTCDR-SLLHNYV---PAGAPK--QIKW-GNNQLADVMGTGQLLLRTRDGES--IWL : 56
N3 : IDSGATHHATPRRLELFSSYEKLETLGDFGADTVKMAGNASFSTVVGIGDVILETMNGMTNTLVL : 65
N4 : MDSGATVHICADRLSMFTSYEKLEYQGSTSADTVLMAGNGSSASVMGIGNVILKLTSGKTNTLVL : 65
N2 : IDSGATHHITSDRLSMFTSYEKLEYQGSTSADTVKMAGNGSSASVMGIGNVILKTTNGHTNTLVL : 65
N7 : LDSGATHHLISDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATKRGIVKLKTHNGHTNTLVL : 65
N6 : LDSGATHHMTSDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATGIGNVKLKTHNGHTNTLVL : 65
N9 : LDSGATHHMTSDRLSMFHNYEKLEPNGSTKADTIKVAGNNQSVSVMGIGNVKLKTHNGHTNTISL : 65
N12 : LDSGASQTLIRSALHHLHNASSNEPNDEIKADTIVVDAQKQNIPINAIGNLQFNFHNGTNNTTSI : 65
N11 : LDSGATHHMTSDALSMLTNYETLEPNDSIKADTIKVAGNGQSVSVMGIGNLKFNFHNGTTNTISI : 65
N16 : LDSGCSRHMTGDRLANFVNLETLELNGSTKADTVTFAGDGSSGRIMGIGTVKVNDKNGTTNTRSL : 65
N17 : LDSGCSRHMTGDRLKNFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGTVKVNDKNGTTNTRSL : 65
N15 : LDSGCSRHMTGDRLANFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGTVKVNDKNGTTNTRSL : 65
N14 : LDSGCSRHMTGDRLANFTNYETLELNGSTKADTVTFAGDGSSGRIMGIGTVKVNDKNGTTNTRSL : 65
N20 : LDSGCTSHMSARRLDWFCSFRTLEEDGGPTADILKLAGDDHSVKSQGQGSIKIETHGGTINTIGL : 65
N21 : IDSGATHHVSHDRLSMFTSYETLELDTSTTSDTVNLAPNGQTVKISGVGTVKLNDHNDTTNTISL : 65
N19 : LDSGCTHHMSHDRLSMFTSYETLELDGSTTADTVKLAGNGQSVKIMGIGTVKLNTHNGTTNTISL : 65
N18 : LDSGCTHHMSHDRLSMFTSYETLELNGSTKADTVKVAGNGQSVRIMGIGTVKLNTHNGTTNTISL : 65
N13 : LDSGCTHHMTSDRLSMFTNYETLELNGSTKADTVKVAGNGQSVRIMGIGTVKLNTHNGTTNTISL : 65
N10 : LDSGATHHMTSDRLSMFTNYETLEPNGSTKADTIKVAGNGQSVSVMGIGNVKLNTHNGTTNTISL : 65
N8 : LDSGATHHMTSDRLSMFTNYEKLEPNGSTKADTIKVAGNGQSVSVMGIGNVKLKTHNGHTNTISL : 65
N5 : LDSGATHHMTSDRLSMFTNYEKLEYNGSTKADTIKVAGNGQSVSVMGIGNVKLKTHNGHTNTLVL : 65
N24 : IDTGATDHITGDLLDKLTTHEKLEYNGGEKADQITAAANGSGMSISHIGNAIVPTPNSRSNTLHL : 65
N23 : IDSGATHHITSDLLNKLTTHEKLEYNGGEKADQITVAANGSGMSISHIGNAILPTPNSRSNTLHL : 65
N22 : IDSGATHHITSDLLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGNVILKTTNGHTNTLVL : 65
N1 : IDSGATHHITSDRLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGNVILKTTNGHTNTLVL : 65
* 80 * 100 *
TNP2 : SDVYYIPQLTTNIVSLGQ-LDE-ARYKVSINDGMMQIREPDRQLLVK- : 99
Opie-2 : KDVALVSKLKYNLLSVSQ-LCD-ENLEVRFKKDRSRVLDASESPVFDI : 98
Endovir : TNVYFVEGLTANLISVSQ-LCD-EGLTVSFNKVKCWATNERNQNTLTG : 97
ToRTL1 : EDVYHVDGLKYSWLSVSQ-ICD-KGNEVKFTSEKCTVVSLTTNKVILT : 93
Sire-1 : --LRYV--KE-DRA-A-Q--CT-RQDKMS-NEELK-LQDP-------- : 75
Ty1 : IKVLHTPNIAYDLLSLNE-LAA--VD-ITACFTKNVLERSDGTVLAPI : 98
Ty2 : K-ALHTPNIAYDLLSLSE-LAN-QNITACFTRNTLERSDGTVLAPIVK : 98
Osser : RNVYYVPGFKFRLLSLKQ-LTN-NGAQFSGSGTSMDVWNSRERWSLYA : 102
Bare1 : SNIFYGHASNVRRLFILNLGSD-NTHIQNIETKRVRVNN-DSTMFLWH : 92
Tnt1 : KDVRHVPDLRMNLISGIA-LDR-DGYESYFANQKWRLTKGSLVIAKGV : 99
Ta1-3 : ENVKYVPELRRNLISTGT-LDK-RGIKHEGGDGKVRYFKNQKTALRGE : 100
Tto1 : RDVRHVPDMRLNLISVDK-LDE-EGYCNTFHNGQVKLTKGSLMVARGT : 100
Evelknieve : KDVLYVPDIQKNLISVYR-MCN-TNGVSVEFFPAHFQVKDLSTGARLL : 101
Hopscotch : RSVLHVPSTHKNLISVHR-LTN-DNDVFIEFHSSHFLIKDRQTKAVLL : 101
Sto-4 : RDVLYVPSLRRNLISVSR-LDD-QHIHCHFGDRQCVICFDNKVGLAIR : 103
Retrofit : NNVLYVPQAKKNLISASQ-LAA-DNSAFLELHSKFFSIKDQVTRDVLL : 101
MelmothAra : KNVLFIPEFRLNLISISS-LTD-DIGSRVIFDKNSCEIQDLIKGRMLG : 97
Melmothbra : HNVLYIPEFRLNLLSISS-LTS-DIGSQVIFDVSSCAIQDPTKGWTIG : 97
Rire1 : KDVLYVPSMSRNLISVSL-LCR-QGLKLVFESNKVVLSKFGTFVGKSY : 101
Fourf : KSVQHVPSIKKNLVSASM-LCR-DGYKVVL-ESNKCVVSKHGTFVGKG : 100
1731 : NNVLFVPDLNGNFMSVSR-AAQ-YKCFVNFGPHYADVIQEGERILRVM : 99
Ty5 : NDVSYVPDLPVNLISIWK-LCAKSNSSVTFTKEGVTVKSPDDVISTAG : 97
Copia : EDVLFCKEAAGNLMSVKR-LQE-AGMSIEFDKSGVTISKNGLMVVKNS : 101
Yokozuna : IEALLVKGLSHNILSVKK-LLE-KGNSVRFHKNSVSIAKGNNIIYGTM : 102
Ty4 : CLTYYVPEEESTIISCYD-LAK-TTKMVLSRKYTRLGNKIIKIKTKIV : 103
Lusen : RNVLHVPSSGLTLMSVDL-LVT-LGCSVTFGTDKAGTYLGPERGTAAH : 102
N3 : KDVRHVPDMRLNLISVDKLLDRKEGYSNTFGNGKVKLTKGSLMVARGT : 113
N4 : KDVLYVPSMRRNLISVSLLLCRKQGYKVVFGNNKVVLTKGNEMVVRTT : 113
N2 : KDVLYVPDMRRNLISVSRLLARKQGYSVTFGNNKVVLTKGNEMVVRTT : 113
N7 : KDVLFVKDLSRNLMSVKRLLAEKQGSSVTFGKNKVVVTKGNEMVVRTT : 113
N6 : KDVLFVPDLSRNLMSVSRLLAEKQGSSVTFGKNKVVVTKGNEMVVRTT : 113
N9 : KDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKVVVTKGNEMVVRTT : 113
N12 : KKVLHTPNIAYDLLSLSELLANKQGSTVTFSRNKLVLSKGNGMVLITT : 113
N11 : KDVLYVPDLRYNLLSLSQLLANKQGSSVTFSKNKVVVTKGNEMVVITT : 113
N16 : KDVYYVPGLKYNLISVSQLLCDKQGSKVSFNEEMCRVTDPNEQVVITT : 113
N17 : KDVYYVPGLKYNLLSVSQLLCDKQGSEVSFNKEKCRVTDPNEQVVITT : 113
N15 : KDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKCRVTDPNEQVVITT : 113
N14 : KDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKCRVTDPNEQVVITT : 113
N20 : ENVKYVPELRRNLISTGTLLDKKRGIKHEGGDGKVRYFKNQKTALRGE : 113
N21 : KNVLYIPEFRLNLISISSLLTNKDIGSQVIFDENSCAIQDPTKGWTIG : 113
N19 : KNVLYVPELRLNLISISSLLTNKQGSSQTFSDEKVRVIKNQKMALTTG : 113
N18 : KDVLYVPDLRLNLISISQLLCNKQGSSVTFSKEKVRVTKPNEMVVTTG : 113
N13 : KDVLYVPDLRYNLISVSQLLCNKQGSSVTFSKEKVRVTKPNEMVVITT : 113
N10 : KDVLYVPDLRYNLISVSQLLANKQGSSVTFSKNKVVVTKGNEMVVITT : 113
N8 : KDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKVVVTKGNEMVVRTT : 113
N5 : KDVLYVPDLRRNLISVSRLLANKQGSSVTFGKNKVVVTKGNEMVVRTT : 113
N24 : KNVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKHFLIKDQETRAVLL : 113
N23 : KDVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKHFLIKDQETGARLL : 113
N22 : KDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKVVLTKDNEMGVRTT : 113
N1 : KDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKVVLTKGNEMVVRTT : 113
Fasta
>TNP2 LDTGTTNHMSGSR-AAFVKLDTA-VLG-----TVRF-GDDPVARIEGHGT VVVCKN-GKL--RSFSDVYYIPQLTTNIVSLGQ-LDE-ARYKVSINDGMM QIREPDRQLLVK- >Opie-2 VDSGCSRHMTGEA-KWFTSLTR--ASSDE---TITF-GDASSGRVMAKGT IKVNDK------FMLKDVALVSKLKYNLLSVSQ-LCD-ENLEVRFKKDRS RVLDASESPVFDI >Endovir FDSGASRHMTGSQ-ANLNNYSS--VKES----NVMF-GGGAKGRIKGKGD LTETEK------PHLTNVYFVEGLTANLISVSQ-LCD-EGLTVSFNKVKC WATNERNQNTLTG >ToRTL1 MDSGCSKHMIGDV-KNFLSLKT--LQGG----GVSF-GDGKNGYILGVGK V------G----RSLEDVYHVDGLKYSWLSVSQ-ICD-KGNEVKFTSEKC TVVSLTTNKVILT >Sire-1 LDSGCSRHMTGVK-EFLVNIE---PCSTS---YVTF-GDGSKGKITGMGK L-VHD--G---------LRYV--KE-DRA-A-Q--CT-RQDKMS-NEELK -LQDP-------- >Ty1 LDSGASRTLIRSA-HHIHSASSN-P-D-----INVVDAQKRNIPINAIGD LQFHF--QDN-TKTSIKVLHTPNIAYDLLSLNE-LAA--VD-ITACFTKN VLERSDGTVLAPI >Ty2 IDSGASQTLVRSA-HYLHHAT---PNSEI---NIVD-AQKQDIPINAIGN LHFNF--GTK--TSIK-ALHTPNIAYDLLSLSE-LAN-QNITACFTRNTL ERSDGTVLAPIVK >Osser LDSGAIYHVTPDA-RSLRDYK---PCDPI---PLKC-GGGEVHYAVGYGD LTYSFHIGPV-VIKIRNVYYVPGFKFRLLSLKQ-LTN-NGAQFSGSGTSM DVWNSRERWSLYA >Bare1 LTSGLVMNLNNCYLVPALSMNI--ISGS----CL-L-RDGYSFKSENNG- -------CS---ISMSNIFYGHASNVRRLFILNLGSD-NTHIQNIETKRV RVNN-DSTMFLWH >Tnt1 VDTAASHHATPVR-DLFCRY----VAGDFG--TVKM-GNTSYSKIAGIGD IITNV--GCT--LVLKDVRHVPDLRMNLISGIA-LDR-DGYESYFANQKW RLTKGSLVIAKGV >Ta1-3 LDSGCTSHMSARR-DWFCSFR---EDGGPT--IL-L-GDDHSVKSQGQGS I-IETHGGTI--IGLENVKYVPELRRNLISTGT-LDK-RGIKHEGGDGKV RYFKNQKTALRGE >Tto1 IDSGATIHATPRR-ELFSSY----TLGDFG--RVKM-GNANFSTVVGKGD V-LETMNGMK--LLLRDVRHVPDMRLNLISVDK-LDE-EGYCNTFHNGQV KLTKGSLMVARGT >Evelknieve LDSGATHHLTSDL-NNLALHQP--YNGGE---EVTI-ADGSGLPISHSGS ALLPTP-TRS--LDLKDVLYVPDIQKNLISVYR-MCN-TNGVSVEFFPAH FQVKDLSTGARLL >Hopscotch TDTGATDHITGDL-DRLTMHDK--YTGTD---QIIA-ANGTGMTISNIGN AIVPTS-SRS--LHLRSVLHVPSTHKNLISVHR-LTN-DNDVFIEFHSSH FLIKDRQTKAVLL >Sto-4 IDSSATVHVANSL-QGLRTSQRL-PKGRR---TIRV-ANGVEAAVEAIGD IHLKLVNGFV--LLLRDVLYVPSLRRNLISVSR-LDD-QHIHCHFGDRQC VICFDNKVGLAIR >Retrofit IDTGATDHITGEL-EKLTTKEK--YNGGE---QIHT-ASGAGMDISHIGH TIVHTP-SRN--IHLNNVLYVPQAKKNLISASQ-LAA-DNSAFLELHSKF FSIKDQVTRDVLL >MelmothAra IDSGATHHVSHDR-SLFSS-----LDTSVLS-AVNL-PTGPTVKISGVGT LKLND--D----ILLKNVLFIPEFRLNLISISS-LTD-DIGSRVIFDKNS CEIQDLIKGRMLG >Melmothbra IDSGATHHVCHDR-SMYTS-----IDITTTS-NVNL-PNGMIVKISGVGI VQLNE--H----ITLHNVLYIPEFRLNLLSISS-LTS-DIGSQVIFDVSS CAIQDPTKGWTIG >Rire1 MDSGATVHICADR-SMFSS-----FQGFNSA-PVLM-GNGVPAAVRGTGQ VYLKLTSGKT--LVLKDVLYVPSMSRNLISVSL-LCR-QGLKLVFESNKV VLSKFGTFVGKSY >Fourf MDSGANIHVCADA-SMFTS-----YQVGRS--GALLMGNGSRAHVLGVGT VILKFTSGKT--VPLKSVQHVPSIKKNLVSASM-LCR-DGYKVVL-ESNK CVVSKHGTFVGKG >1731 LDSGATSHMCCDR-SVFTE-----FEEHTE--KISLAGNG-FLLAKGIGT VKLKTD-LCT--LVLNNVLFVPDLNGNFMSVSR-AAQ-YKCFVNFGPHYA DVIQEGERILRVM >Ty5 FDTGCTSHMCHDR-SMFSS-----FTRSSKKDFVRG-VGG-SIPIMGSGT V--NI--GT---VQLNDVSYVPDLPVNLISIWK-LCAKSNSSVTFTKEGV TVKSPDDVISTAG >Copia LDSGASDHLINDE-SLYTDSVELVPPL-----KIAVAKQGEFIYATKRGI VRLRN--DHE--ITLEDVLFCKEAAGNLMSVKR-LQE-AGMSIEFDKSGV TISKNGLMVVKNS >Yokozuna IDSGASQNLVID--SYEKYMSNIEYLETKT--KIYV-ANGQYLFSSKKGI LNVKY---NN-LPIKIEALLVKGLSHNILSVKK-LLE-KGNSVRFHKNSV SIAKGNNIIYGTM >Ty4 IDTGSGVNITNDK-TLLHNYED--SNRSTR--FFGI-GKNSSVSVKGYGY IKIKN--GHNNTDNKCLTYYVPEEESTIISCYD-LAK-TTKMVLSRKYTR LGNKIIKIKTKIV >Lusen LDSGSPYHLTCDR-SLLHNYV---PAGAPK--QIKW-GNNQLADVMGTGQ LLLRTRDGES--IWLRNVLHVPSSGLTLMSVDL-LVT-LGCSVTFGTDKA GTYLGPERGTAAH >N3 IDSGATHHATPRRLELFSSYEKLETLGDFGADTVKMAGNASFSTVVGIGD VILETMNGMTNTLVLKDVRHVPDMRLNLISVDKLLDRKEGYSNTFGNGKV KLTKGSLMVARGT >N4 MDSGATVHICADRLSMFTSYEKLEYQGSTSADTVLMAGNGSSASVMGIGN VILKLTSGKTNTLVLKDVLYVPSMRRNLISVSLLLCRKQGYKVVFGNNKV VLTKGNEMVVRTT >N2 IDSGATHHITSDRLSMFTSYEKLEYQGSTSADTVKMAGNGSSASVMGIGN VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLARKQGYSVTFGNNKV VLTKGNEMVVRTT >N7 LDSGATHHLISDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATKRGI VKLKTHNGHTNTLVLKDVLFVKDLSRNLMSVKRLLAEKQGSSVTFGKNKV VVTKGNEMVVRTT >N6 LDSGATHHMTSDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATGIGN VKLKTHNGHTNTLVLKDVLFVPDLSRNLMSVSRLLAEKQGSSVTFGKNKV VVTKGNEMVVRTT >N9 LDSGATHHMTSDRLSMFHNYEKLEPNGSTKADTIKVAGNNQSVSVMGIGN VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV VVTKGNEMVVRTT >N12 LDSGASQTLIRSALHHLHNASSNEPNDEIKADTIVVDAQKQNIPINAIGN LQFNFHNGTNNTTSIKKVLHTPNIAYDLLSLSELLANKQGSTVTFSRNKL VLSKGNGMVLITT >N11 LDSGATHHMTSDALSMLTNYETLEPNDSIKADTIKVAGNGQSVSVMGIGN LKFNFHNGTTNTISIKDVLYVPDLRYNLLSLSQLLANKQGSSVTFSKNKV VVTKGNEMVVITT >N16 LDSGCSRHMTGDRLANFVNLETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNEEMC RVTDPNEQVVITT >N17 LDSGCSRHMTGDRLKNFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLLSVSQLLCDKQGSEVSFNKEKC RVTDPNEQVVITT >N15 LDSGCSRHMTGDRLANFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC RVTDPNEQVVITT >N14 LDSGCSRHMTGDRLANFTNYETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC RVTDPNEQVVITT >N20 LDSGCTSHMSARRLDWFCSFRTLEEDGGPTADILKLAGDDHSVKSQGQGS IKIETHGGTINTIGLENVKYVPELRRNLISTGTLLDKKRGIKHEGGDGKV RYFKNQKTALRGE >N21 IDSGATHHVSHDRLSMFTSYETLELDTSTTSDTVNLAPNGQTVKISGVGT VKLNDHNDTTNTISLKNVLYIPEFRLNLISISSLLTNKDIGSQVIFDENS CAIQDPTKGWTIG >N19 LDSGCTHHMSHDRLSMFTSYETLELDGSTTADTVKLAGNGQSVKIMGIGT VKLNTHNGTTNTISLKNVLYVPELRLNLISISSLLTNKQGSSQTFSDEKV RVIKNQKMALTTG >N18 LDSGCTHHMSHDRLSMFTSYETLELNGSTKADTVKVAGNGQSVRIMGIGT VKLNTHNGTTNTISLKDVLYVPDLRLNLISISQLLCNKQGSSVTFSKEKV RVTKPNEMVVTTG >N13 LDSGCTHHMTSDRLSMFTNYETLELNGSTKADTVKVAGNGQSVRIMGIGT VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLCNKQGSSVTFSKEKV RVTKPNEMVVITT >N10 LDSGATHHMTSDRLSMFTNYETLEPNGSTKADTIKVAGNGQSVSVMGIGN VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLANKQGSSVTFSKNKV VVTKGNEMVVITT >N8 LDSGATHHMTSDRLSMFTNYEKLEPNGSTKADTIKVAGNGQSVSVMGIGN VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV VVTKGNEMVVRTT >N5 LDSGATHHMTSDRLSMFTNYEKLEYNGSTKADTIKVAGNGQSVSVMGIGN VKLKTHNGHTNTLVLKDVLYVPDLRRNLISVSRLLANKQGSSVTFGKNKV VVTKGNEMVVRTT >N24 IDTGATDHITGDLLDKLTTHEKLEYNGGEKADQITAAANGSGMSISHIGN AIVPTPNSRSNTLHLKNVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH FLIKDQETRAVLL >N23 IDSGATHHITSDLLNKLTTHEKLEYNGGEKADQITVAANGSGMSISHIGN AILPTPNSRSNTLHLKDVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH FLIKDQETGARLL >N22 IDSGATHHITSDLLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV VLTKDNEMGVRTT >N1 IDSGATHHITSDRLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV VLTKGNEMVVRTT
PIR
>P1;TNP2 LDTGTTNHMSGSR-AAFVKLDTA-VLG-----TVRF-GDDPVARIEGHGT VVVCKN-GKL--RSFSDVYYIPQLTTNIVSLGQ-LDE-ARYKVSINDGMM QIREPDRQLLVK- * >P1;Opie-2 VDSGCSRHMTGEA-KWFTSLTR--ASSDE---TITF-GDASSGRVMAKGT IKVNDK------FMLKDVALVSKLKYNLLSVSQ-LCD-ENLEVRFKKDRS RVLDASESPVFDI * >P1;Endovir FDSGASRHMTGSQ-ANLNNYSS--VKES----NVMF-GGGAKGRIKGKGD LTETEK------PHLTNVYFVEGLTANLISVSQ-LCD-EGLTVSFNKVKC WATNERNQNTLTG * >P1;ToRTL1 MDSGCSKHMIGDV-KNFLSLKT--LQGG----GVSF-GDGKNGYILGVGK V------G----RSLEDVYHVDGLKYSWLSVSQ-ICD-KGNEVKFTSEKC TVVSLTTNKVILT * >P1;Sire-1 LDSGCSRHMTGVK-EFLVNIE---PCSTS---YVTF-GDGSKGKITGMGK L-VHD--G---------LRYV--KE-DRA-A-Q--CT-RQDKMS-NEELK -LQDP-------- * >P1;Ty1 LDSGASRTLIRSA-HHIHSASSN-P-D-----INVVDAQKRNIPINAIGD LQFHF--QDN-TKTSIKVLHTPNIAYDLLSLNE-LAA--VD-ITACFTKN VLERSDGTVLAPI * >P1;Ty2 IDSGASQTLVRSA-HYLHHAT---PNSEI---NIVD-AQKQDIPINAIGN LHFNF--GTK--TSIK-ALHTPNIAYDLLSLSE-LAN-QNITACFTRNTL ERSDGTVLAPIVK * >P1;Osser LDSGAIYHVTPDA-RSLRDYK---PCDPI---PLKC-GGGEVHYAVGYGD LTYSFHIGPV-VIKIRNVYYVPGFKFRLLSLKQ-LTN-NGAQFSGSGTSM DVWNSRERWSLYA * >P1;Bare1 LTSGLVMNLNNCYLVPALSMNI--ISGS----CL-L-RDGYSFKSENNG- -------CS---ISMSNIFYGHASNVRRLFILNLGSD-NTHIQNIETKRV RVNN-DSTMFLWH * >P1;Tnt1 VDTAASHHATPVR-DLFCRY----VAGDFG--TVKM-GNTSYSKIAGIGD IITNV--GCT--LVLKDVRHVPDLRMNLISGIA-LDR-DGYESYFANQKW RLTKGSLVIAKGV * >P1;Ta1-3 LDSGCTSHMSARR-DWFCSFR---EDGGPT--IL-L-GDDHSVKSQGQGS I-IETHGGTI--IGLENVKYVPELRRNLISTGT-LDK-RGIKHEGGDGKV RYFKNQKTALRGE * >P1;Tto1 IDSGATIHATPRR-ELFSSY----TLGDFG--RVKM-GNANFSTVVGKGD V-LETMNGMK--LLLRDVRHVPDMRLNLISVDK-LDE-EGYCNTFHNGQV KLTKGSLMVARGT * >P1;Evelknieve LDSGATHHLTSDL-NNLALHQP--YNGGE---EVTI-ADGSGLPISHSGS ALLPTP-TRS--LDLKDVLYVPDIQKNLISVYR-MCN-TNGVSVEFFPAH FQVKDLSTGARLL * >P1;Hopscotch TDTGATDHITGDL-DRLTMHDK--YTGTD---QIIA-ANGTGMTISNIGN AIVPTS-SRS--LHLRSVLHVPSTHKNLISVHR-LTN-DNDVFIEFHSSH FLIKDRQTKAVLL * >P1;Sto-4 IDSSATVHVANSL-QGLRTSQRL-PKGRR---TIRV-ANGVEAAVEAIGD IHLKLVNGFV--LLLRDVLYVPSLRRNLISVSR-LDD-QHIHCHFGDRQC VICFDNKVGLAIR * >P1;Retrofit IDTGATDHITGEL-EKLTTKEK--YNGGE---QIHT-ASGAGMDISHIGH TIVHTP-SRN--IHLNNVLYVPQAKKNLISASQ-LAA-DNSAFLELHSKF FSIKDQVTRDVLL * >P1;MelmothAra IDSGATHHVSHDR-SLFSS-----LDTSVLS-AVNL-PTGPTVKISGVGT LKLND--D----ILLKNVLFIPEFRLNLISISS-LTD-DIGSRVIFDKNS CEIQDLIKGRMLG * >P1;Melmothbra IDSGATHHVCHDR-SMYTS-----IDITTTS-NVNL-PNGMIVKISGVGI VQLNE--H----ITLHNVLYIPEFRLNLLSISS-LTS-DIGSQVIFDVSS CAIQDPTKGWTIG * >P1;Rire1 MDSGATVHICADR-SMFSS-----FQGFNSA-PVLM-GNGVPAAVRGTGQ VYLKLTSGKT--LVLKDVLYVPSMSRNLISVSL-LCR-QGLKLVFESNKV VLSKFGTFVGKSY * >P1;Fourf MDSGANIHVCADA-SMFTS-----YQVGRS--GALLMGNGSRAHVLGVGT VILKFTSGKT--VPLKSVQHVPSIKKNLVSASM-LCR-DGYKVVL-ESNK CVVSKHGTFVGKG * >P1;1731 LDSGATSHMCCDR-SVFTE-----FEEHTE--KISLAGNG-FLLAKGIGT VKLKTD-LCT--LVLNNVLFVPDLNGNFMSVSR-AAQ-YKCFVNFGPHYA DVIQEGERILRVM * >P1;Ty5 FDTGCTSHMCHDR-SMFSS-----FTRSSKKDFVRG-VGG-SIPIMGSGT V--NI--GT---VQLNDVSYVPDLPVNLISIWK-LCAKSNSSVTFTKEGV TVKSPDDVISTAG * >P1;Copia LDSGASDHLINDE-SLYTDSVELVPPL-----KIAVAKQGEFIYATKRGI VRLRN--DHE--ITLEDVLFCKEAAGNLMSVKR-LQE-AGMSIEFDKSGV TISKNGLMVVKNS * >P1;Yokozuna IDSGASQNLVID--SYEKYMSNIEYLETKT--KIYV-ANGQYLFSSKKGI LNVKY---NN-LPIKIEALLVKGLSHNILSVKK-LLE-KGNSVRFHKNSV SIAKGNNIIYGTM * >P1;Ty4 IDTGSGVNITNDK-TLLHNYED--SNRSTR--FFGI-GKNSSVSVKGYGY IKIKN--GHNNTDNKCLTYYVPEEESTIISCYD-LAK-TTKMVLSRKYTR LGNKIIKIKTKIV * >P1;Lusen LDSGSPYHLTCDR-SLLHNYV---PAGAPK--QIKW-GNNQLADVMGTGQ LLLRTRDGES--IWLRNVLHVPSSGLTLMSVDL-LVT-LGCSVTFGTDKA GTYLGPERGTAAH * >P1;N3 IDSGATHHATPRRLELFSSYEKLETLGDFGADTVKMAGNASFSTVVGIGD VILETMNGMTNTLVLKDVRHVPDMRLNLISVDKLLDRKEGYSNTFGNGKV KLTKGSLMVARGT * >P1;N4 MDSGATVHICADRLSMFTSYEKLEYQGSTSADTVLMAGNGSSASVMGIGN VILKLTSGKTNTLVLKDVLYVPSMRRNLISVSLLLCRKQGYKVVFGNNKV VLTKGNEMVVRTT * >P1;N2 IDSGATHHITSDRLSMFTSYEKLEYQGSTSADTVKMAGNGSSASVMGIGN VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLARKQGYSVTFGNNKV VLTKGNEMVVRTT * >P1;N7 LDSGATHHLISDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATKRGI VKLKTHNGHTNTLVLKDVLFVKDLSRNLMSVKRLLAEKQGSSVTFGKNKV VVTKGNEMVVRTT * >P1;N6 LDSGATHHMTSDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATGIGN VKLKTHNGHTNTLVLKDVLFVPDLSRNLMSVSRLLAEKQGSSVTFGKNKV VVTKGNEMVVRTT * >P1;N9 LDSGATHHMTSDRLSMFHNYEKLEPNGSTKADTIKVAGNNQSVSVMGIGN VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV VVTKGNEMVVRTT * >P1;N12 LDSGASQTLIRSALHHLHNASSNEPNDEIKADTIVVDAQKQNIPINAIGN LQFNFHNGTNNTTSIKKVLHTPNIAYDLLSLSELLANKQGSTVTFSRNKL VLSKGNGMVLITT * >P1;N11 LDSGATHHMTSDALSMLTNYETLEPNDSIKADTIKVAGNGQSVSVMGIGN LKFNFHNGTTNTISIKDVLYVPDLRYNLLSLSQLLANKQGSSVTFSKNKV VVTKGNEMVVITT * >P1;N16 LDSGCSRHMTGDRLANFVNLETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNEEMC RVTDPNEQVVITT * >P1;N17 LDSGCSRHMTGDRLKNFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLLSVSQLLCDKQGSEVSFNKEKC RVTDPNEQVVITT * >P1;N15 LDSGCSRHMTGDRLANFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC RVTDPNEQVVITT * >P1;N14 LDSGCSRHMTGDRLANFTNYETLELNGSTKADTVTFAGDGSSGRIMGIGT VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC RVTDPNEQVVITT * >P1;N20 LDSGCTSHMSARRLDWFCSFRTLEEDGGPTADILKLAGDDHSVKSQGQGS IKIETHGGTINTIGLENVKYVPELRRNLISTGTLLDKKRGIKHEGGDGKV RYFKNQKTALRGE * >P1;N21 IDSGATHHVSHDRLSMFTSYETLELDTSTTSDTVNLAPNGQTVKISGVGT VKLNDHNDTTNTISLKNVLYIPEFRLNLISISSLLTNKDIGSQVIFDENS CAIQDPTKGWTIG * >P1;N19 LDSGCTHHMSHDRLSMFTSYETLELDGSTTADTVKLAGNGQSVKIMGIGT VKLNTHNGTTNTISLKNVLYVPELRLNLISISSLLTNKQGSSQTFSDEKV RVIKNQKMALTTG * >P1;N18 LDSGCTHHMSHDRLSMFTSYETLELNGSTKADTVKVAGNGQSVRIMGIGT VKLNTHNGTTNTISLKDVLYVPDLRLNLISISQLLCNKQGSSVTFSKEKV RVTKPNEMVVTTG * >P1;N13 LDSGCTHHMTSDRLSMFTNYETLELNGSTKADTVKVAGNGQSVRIMGIGT VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLCNKQGSSVTFSKEKV RVTKPNEMVVITT * >P1;N10 LDSGATHHMTSDRLSMFTNYETLEPNGSTKADTIKVAGNGQSVSVMGIGN VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLANKQGSSVTFSKNKV VVTKGNEMVVITT * >P1;N8 LDSGATHHMTSDRLSMFTNYEKLEPNGSTKADTIKVAGNGQSVSVMGIGN VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV VVTKGNEMVVRTT * >P1;N5 LDSGATHHMTSDRLSMFTNYEKLEYNGSTKADTIKVAGNGQSVSVMGIGN VKLKTHNGHTNTLVLKDVLYVPDLRRNLISVSRLLANKQGSSVTFGKNKV VVTKGNEMVVRTT * >P1;N24 IDTGATDHITGDLLDKLTTHEKLEYNGGEKADQITAAANGSGMSISHIGN AIVPTPNSRSNTLHLKNVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH FLIKDQETRAVLL * >P1;N23 IDSGATHHITSDLLNKLTTHEKLEYNGGEKADQITVAANGSGMSISHIGN AILPTPNSRSNTLHLKDVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH FLIKDQETGARLL * >P1;N22 IDSGATHHITSDLLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV VLTKDNEMGVRTT * >P1;N1 IDSGATHHITSDRLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV VLTKGNEMVVRTT *
Philyp
50 113
TNP2 LDTGTTNHMS GSR-AAFVKL DTA-VLG--- --TVRF-GDD PVARIEGHGT
Opie-2 VDSGCSRHMT GEA-KWFTSL TR--ASSDE- --TITF-GDA SSGRVMAKGT
Endovir FDSGASRHMT GSQ-ANLNNY SS--VKES-- --NVMF-GGG AKGRIKGKGD
ToRTL1 MDSGCSKHMI GDV-KNFLSL KT--LQGG-- --GVSF-GDG KNGYILGVGK
Sire-1 LDSGCSRHMT GVK-EFLVNI E---PCSTS- --YVTF-GDG SKGKITGMGK
Ty1 LDSGASRTLI RSA-HHIHSA SSN-P-D--- --INVVDAQK RNIPINAIGD
Ty2 IDSGASQTLV RSA-HYLHHA T---PNSEI- --NIVD-AQK QDIPINAIGN
Osser LDSGAIYHVT PDA-RSLRDY K---PCDPI- --PLKC-GGG EVHYAVGYGD
Bare1 LTSGLVMNLN NCYLVPALSM NI--ISGS-- --CL-L-RDG YSFKSENNG-
Tnt1 VDTAASHHAT PVR-DLFCRY ----VAGDFG --TVKM-GNT SYSKIAGIGD
Ta1-3 LDSGCTSHMS ARR-DWFCSF R---EDGGPT --IL-L-GDD HSVKSQGQGS
Tto1 IDSGATIHAT PRR-ELFSSY ----TLGDFG --RVKM-GNA NFSTVVGKGD
Evelknieve LDSGATHHLT SDL-NNLALH QP--YNGGE- --EVTI-ADG SGLPISHSGS
Hopscotch TDTGATDHIT GDL-DRLTMH DK--YTGTD- --QIIA-ANG TGMTISNIGN
Sto-4 IDSSATVHVA NSL-QGLRTS QRL-PKGRR- --TIRV-ANG VEAAVEAIGD
Retrofit IDTGATDHIT GEL-EKLTTK EK--YNGGE- --QIHT-ASG AGMDISHIGH
MelmothAra IDSGATHHVS HDR-SLFSS- ----LDTSVL S-AVNL-PTG PTVKISGVGT
Melmothbra IDSGATHHVC HDR-SMYTS- ----IDITTT S-NVNL-PNG MIVKISGVGI
Rire1 MDSGATVHIC ADR-SMFSS- ----FQGFNS A-PVLM-GNG VPAAVRGTGQ
Fourf MDSGANIHVC ADA-SMFTS- ----YQVGRS --GALLMGNG SRAHVLGVGT
1731 LDSGATSHMC CDR-SVFTE- ----FEEHTE --KISLAGNG -FLLAKGIGT
Ty5 FDTGCTSHMC HDR-SMFSS- ----FTRSSK KDFVRG-VGG -SIPIMGSGT
Copia LDSGASDHLI NDE-SLYTDS VELVPPL--- --KIAVAKQG EFIYATKRGI
Yokozuna IDSGASQNLV ID--SYEKYM SNIEYLETKT --KIYV-ANG QYLFSSKKGI
Ty4 IDTGSGVNIT NDK-TLLHNY ED--SNRSTR --FFGI-GKN SSVSVKGYGY
Lusen LDSGSPYHLT CDR-SLLHNY V---PAGAPK --QIKW-GNN QLADVMGTGQ
N3 IDSGATHHAT PRRLELFSSY EKLETLGDFG ADTVKMAGNA SFSTVVGIGD
N4 MDSGATVHIC ADRLSMFTSY EKLEYQGSTS ADTVLMAGNG SSASVMGIGN
N2 IDSGATHHIT SDRLSMFTSY EKLEYQGSTS ADTVKMAGNG SSASVMGIGN
N7 LDSGATHHLI SDRLSMFTNY EKLEYNESTK ADKISVAGNG QFVFATKRGI
N6 LDSGATHHMT SDRLSMFTNY EKLEYNESTK ADKISVAGNG QFVFATGIGN
N9 LDSGATHHMT SDRLSMFHNY EKLEPNGSTK ADTIKVAGNN QSVSVMGIGN
N12 LDSGASQTLI RSALHHLHNA SSNEPNDEIK ADTIVVDAQK QNIPINAIGN
N11 LDSGATHHMT SDALSMLTNY ETLEPNDSIK ADTIKVAGNG QSVSVMGIGN
N16 LDSGCSRHMT GDRLANFVNL ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N17 LDSGCSRHMT GDRLKNFTNL ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N15 LDSGCSRHMT GDRLANFTNL ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N14 LDSGCSRHMT GDRLANFTNY ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N20 LDSGCTSHMS ARRLDWFCSF RTLEEDGGPT ADILKLAGDD HSVKSQGQGS
N21 IDSGATHHVS HDRLSMFTSY ETLELDTSTT SDTVNLAPNG QTVKISGVGT
N19 LDSGCTHHMS HDRLSMFTSY ETLELDGSTT ADTVKLAGNG QSVKIMGIGT
N18 LDSGCTHHMS HDRLSMFTSY ETLELNGSTK ADTVKVAGNG QSVRIMGIGT
N13 LDSGCTHHMT SDRLSMFTNY ETLELNGSTK ADTVKVAGNG QSVRIMGIGT
N10 LDSGATHHMT SDRLSMFTNY ETLEPNGSTK ADTIKVAGNG QSVSVMGIGN
N8 LDSGATHHMT SDRLSMFTNY EKLEPNGSTK ADTIKVAGNG QSVSVMGIGN
N5 LDSGATHHMT SDRLSMFTNY EKLEYNGSTK ADTIKVAGNG QSVSVMGIGN
N24 IDTGATDHIT GDLLDKLTTH EKLEYNGGEK ADQITAAANG SGMSISHIGN
N23 IDSGATHHIT SDLLNKLTTH EKLEYNGGEK ADQITVAANG SGMSISHIGN
N22 IDSGATHHIT SDLLSMFTSY EKLEYNGSTK ADTIKVAGNG SSASVMGIGN
N1 IDSGATHHIT SDRLSMFTSY EKLEYNGSTK ADTIKVAGNG SSASVMGIGN
VVVCKN-GKL --RSFSDVYY IPQLTTNIVS LGQ-LDE-AR YKVSINDGMM
IKVNDK---- --FMLKDVAL VSKLKYNLLS VSQ-LCD-EN LEVRFKKDRS
LTETEK---- --PHLTNVYF VEGLTANLIS VSQ-LCD-EG LTVSFNKVKC
V------G-- --RSLEDVYH VDGLKYSWLS VSQ-ICD-KG NEVKFTSEKC
L-VHD--G-- -------LRY V--KE-DRA- A-Q--CT-RQ DKMS-NEELK
LQFHF--QDN -TKTSIKVLH TPNIAYDLLS LNE-LAA--V D-ITACFTKN
LHFNF--GTK --TSIK-ALH TPNIAYDLLS LSE-LAN-QN ITACFTRNTL
LTYSFHIGPV -VIKIRNVYY VPGFKFRLLS LKQ-LTN-NG AQFSGSGTSM
-------CS- --ISMSNIFY GHASNVRRLF ILNLGSD-NT HIQNIETKRV
IITNV--GCT --LVLKDVRH VPDLRMNLIS GIA-LDR-DG YESYFANQKW
I-IETHGGTI --IGLENVKY VPELRRNLIS TGT-LDK-RG IKHEGGDGKV
V-LETMNGMK --LLLRDVRH VPDMRLNLIS VDK-LDE-EG YCNTFHNGQV
ALLPTP-TRS --LDLKDVLY VPDIQKNLIS VYR-MCN-TN GVSVEFFPAH
AIVPTS-SRS --LHLRSVLH VPSTHKNLIS VHR-LTN-DN DVFIEFHSSH
IHLKLVNGFV --LLLRDVLY VPSLRRNLIS VSR-LDD-QH IHCHFGDRQC
TIVHTP-SRN --IHLNNVLY VPQAKKNLIS ASQ-LAA-DN SAFLELHSKF
LKLND--D-- --ILLKNVLF IPEFRLNLIS ISS-LTD-DI GSRVIFDKNS
VQLNE--H-- --ITLHNVLY IPEFRLNLLS ISS-LTS-DI GSQVIFDVSS
VYLKLTSGKT --LVLKDVLY VPSMSRNLIS VSL-LCR-QG LKLVFESNKV
VILKFTSGKT --VPLKSVQH VPSIKKNLVS ASM-LCR-DG YKVVL-ESNK
VKLKTD-LCT --LVLNNVLF VPDLNGNFMS VSR-AAQ-YK CFVNFGPHYA
V--NI--GT- --VQLNDVSY VPDLPVNLIS IWK-LCAKSN SSVTFTKEGV
VRLRN--DHE --ITLEDVLF CKEAAGNLMS VKR-LQE-AG MSIEFDKSGV
LNVKY---NN -LPIKIEALL VKGLSHNILS VKK-LLE-KG NSVRFHKNSV
IKIKN--GHN NTDNKCLTYY VPEEESTIIS CYD-LAK-TT KMVLSRKYTR
LLLRTRDGES --IWLRNVLH VPSSGLTLMS VDL-LVT-LG CSVTFGTDKA
VILETMNGMT NTLVLKDVRH VPDMRLNLIS VDKLLDRKEG YSNTFGNGKV
VILKLTSGKT NTLVLKDVLY VPSMRRNLIS VSLLLCRKQG YKVVFGNNKV
VILKTTNGHT NTLVLKDVLY VPDMRRNLIS VSRLLARKQG YSVTFGNNKV
VKLKTHNGHT NTLVLKDVLF VKDLSRNLMS VKRLLAEKQG SSVTFGKNKV
VKLKTHNGHT NTLVLKDVLF VPDLSRNLMS VSRLLAEKQG SSVTFGKNKV
VKLKTHNGHT NTISLKDVLY VPDLRRNLIS VSQLLANKQG SSVTFGKNKV
LQFNFHNGTN NTTSIKKVLH TPNIAYDLLS LSELLANKQG STVTFSRNKL
LKFNFHNGTT NTISIKDVLY VPDLRYNLLS LSQLLANKQG SSVTFSKNKV
VKVNDKNGTT NTRSLKDVYY VPGLKYNLIS VSQLLCDKQG SKVSFNEEMC
VKVNDKNGTT NTRSLKDVYY VPGLKYNLLS VSQLLCDKQG SEVSFNKEKC
VKVNDKNGTT NTRSLKDVYY VPGLKYNLIS VSQLLCDKQG SKVSFNKEKC
VKVNDKNGTT NTRSLKDVYY VPGLKYNLIS VSQLLCDKQG SKVSFNKEKC
IKIETHGGTI NTIGLENVKY VPELRRNLIS TGTLLDKKRG IKHEGGDGKV
VKLNDHNDTT NTISLKNVLY IPEFRLNLIS ISSLLTNKDI GSQVIFDENS
VKLNTHNGTT NTISLKNVLY VPELRLNLIS ISSLLTNKQG SSQTFSDEKV
VKLNTHNGTT NTISLKDVLY VPDLRLNLIS ISQLLCNKQG SSVTFSKEKV
VKLNTHNGTT NTISLKDVLY VPDLRYNLIS VSQLLCNKQG SSVTFSKEKV
VKLNTHNGTT NTISLKDVLY VPDLRYNLIS VSQLLANKQG SSVTFSKNKV
VKLKTHNGHT NTISLKDVLY VPDLRRNLIS VSQLLANKQG SSVTFGKNKV
VKLKTHNGHT NTLVLKDVLY VPDLRRNLIS VSRLLANKQG SSVTFGKNKV
AIVPTPNSRS NTLHLKNVLY VPDTRKNLIS VSRLLANKDN SVFIEFHSKH
AILPTPNSRS NTLHLKDVLY VPDTRKNLIS VSRLLANKDN SVFIEFHSKH
VILKTTNGHT NTLVLKDVLY VPDMRRNLIS VSRLLANKQG SSVTFGNNKV
VILKTTNGHT NTLVLKDVLY VPDMRRNLIS VSRLLANKQG SSVTFGNNKV
QIREPDRQLL VK-
RVLDASESPV FDI
WATNERNQNT LTG
TVVSLTTNKV ILT
-LQDP----- ---
VLERSDGTVL API
ERSDGTVLAP IVK
DVWNSRERWS LYA
RVNN-DSTMF LWH
RLTKGSLVIA KGV
RYFKNQKTAL RGE
KLTKGSLMVA RGT
FQVKDLSTGA RLL
FLIKDRQTKA VLL
VICFDNKVGL AIR
FSIKDQVTRD VLL
CEIQDLIKGR MLG
CAIQDPTKGW TIG
VLSKFGTFVG KSY
CVVSKHGTFV GKG
DVIQEGERIL RVM
TVKSPDDVIS TAG
TISKNGLMVV KNS
SIAKGNNIIY GTM
LGNKIIKIKT KIV
GTYLGPERGT AAH
KLTKGSLMVA RGT
VLTKGNEMVV RTT
VLTKGNEMVV RTT
VVTKGNEMVV RTT
VVTKGNEMVV RTT
VVTKGNEMVV RTT
VLSKGNGMVL ITT
VVTKGNEMVV ITT
RVTDPNEQVV ITT
RVTDPNEQVV ITT
RVTDPNEQVV ITT
RVTDPNEQVV ITT
RYFKNQKTAL RGE
CAIQDPTKGW TIG
RVIKNQKMAL TTG
RVTKPNEMVV TTG
RVTKPNEMVV ITT
VVTKGNEMVV ITT
VVTKGNEMVV RTT
VVTKGNEMVV RTT
FLIKDQETRA VLL
FLIKDQETGA RLL
VLTKDNEMGV RTT
VLTKGNEMVV RTT
MSF
PileUp
GDC ******** GeneDoc Multiple Sequence Alignment Editor ********
GDC 010af90190000cffffffffffff000000000000000000808080c0c0c0ffff
GDC ff000000000000f43f000000000000f43f000000000000f03f0000000000
GDC 00f03f00A000300000190000cA54696d6573204e657720526f6d616e00A0
GDC 0320002000000000000000000000401444e45510002535400034b5248000
GDC 44c49564d4659574750410028544e50322c0d0a4f7069652d322c0d0a456
GDC e646f7669722c0d0a546f52544c312c0d0a536972652d312c0d0a5479312
GDC c0d0a5479322c0d0a4f737365722c0d0a42617265312c0d0a546e74312c0
GDC d0a5461312d332c0d0a54746f312c0d0a4576656c6b6e696576652c0d0a4
GDC 86f7073636f7463682c0d0a53746f2d342c0d0a526574726f6669742c0d0
GDC a4d656c6d6f74684172612c0d0a4d656c6d6f74686272612c0d0a5269726
GDC 5312c0d0a466f7572662c0d0a313733312c0d0a5479352c0d0a436f70696
GDC 12c0d0a596f6b6f7a756e612c0d0a5479342c0d0a4c7573656e2c0d0a4e3
GDC 32c0d0a4e342c0d0a4e322c0d0a4e372c0d0a4e362c0d0a4e392c0d0a4e3
GDC 1322c0d0a4e31312c0d0a4e31362c0d0a4e31372c0d0a4e31352c0d0a4e3
GDC 1342c0d0a4e32302c0d0a4e32312c0d0a4e31392c0d0a4e31382c0d0a4e3
GDC 1332c0d0a4e31302c0d0a4e382c0d0a4e352c0d0a4e32342c0d0a4e32332
GDC c0d0a4e32322c0d0a4e31293b0d0a00BBAABAAA0000002a000a00020001B
GDC 20AAA000a203a2000203a200000000000000059400000000000000000000
GDC c5058000000ffff000047580000ff00ff000041475358000000ffffff005
GDC 6434147444e535450580000ff00ffff00484b525800ff00000000ff45445
GDC 80000ff000000ff484b5245445800ffffff0000ff48524551444e425a580
GDC 0ff000000ff005957484b524551444e5354425a580000000000ff00494c5
GDC 6415800ff00008080804659574858000000ff808080494c564341474d465
GDC 9574854505800ffffff0000000c505800000000ffffff47580054541b000
GDC 000414347535800ffffff440000564147444e53545058000000000000004
GDC 84b5258004500004e4e1b45445800ffffff808080484b52454458004c4c1
GDC b00000048524551444e425a5800ffffff470000435957484b524551444e5
GDC 354425a5800000000000000494c5641580048000056561b4659574858000
GDC 00000ffffff494c564341474d465957485450580049491b0000000300fff
GDC fff00000000ffffff80808000000000c0c0c00000ABBBBBBBBBBBBBB00ff
GDC 00A003200010001000100010001000100010001000100010001000100010
GDC 001000100010001000100010001000100010001000100010001000100010
GDC 001000100010001000100010001000100010001000100010001000100010
GDC 001000100010001000100010001A0018AA000000000000000000000003A0
GDC 0ff00A000000000080564000000000008051400000000000004940000002
GDC 0000000000001440A0000000098b20c41000000001025064100000000189
GDC 806410000000078b10b4100AAABB00005374616e646172640046464c4c53
GDC 53535359592a2a43432a574c4c4c4c505050504848515152525252494949
GDC 4d545454544e4e4b4b535352525656565641414141444445454747474700
GDC 2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d
GDC 2d2d2d2d2d4d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d2d
GDC 2d2d2d2d00BBBBB000000000000003200000000000000000000000000000
GDC 000000000000000000000000000000000000000000000000000000000000
GDC 000000000000000000000000000000000000000000000000000000000000
GDC 000000000000000000000000000000000000000000000000000000300000
GDC 0000000BBAB0032000000000000000000000000000000000000000000000
GDC 00000000000000000000000000000000000000000000000000000000201b
GDC 7B000000000000594000000000000054400000000000004e4000DAAB0000
GDC 00ffffff0302014445484b524e5153540000ff00ff0000024c49564d4659
GDC 574147435000ff000000ff0004014445484b520000ff00ff0000024e5153
GDC 540000ff00ff8000034c49564d46595700ff000000ff0004414700ff0000
GDC 008000080144450000ff00ff000002484b5200ffffffff0000034e510000
GDC ff00ff800004535400ffffffff8000054c495600ff000000ff0006465957
GDC 00ffffff00ff0007414700ff0000008000084d4300ffffff008000000000
GDC 0000Affffff80808000A
ty1_copia.msf MSF: 113 Type: P November 7, 2007 13:33 Check: 7497 ..
Name: TNP2 Len: 113 Check: 7190 Weight: 0.00
Name: Opie-2 Len: 113 Check: 7971 Weight: 100.00
Name: Endovir Len: 113 Check: 7537 Weight: 100.00
Name: ToRTL1 Len: 113 Check: 2199 Weight: 100.00
Name: Sire-1 Len: 113 Check: 3212 Weight: 100.00
Name: Ty1 Len: 113 Check: 1413 Weight: 100.00
Name: Ty2 Len: 113 Check: 3882 Weight: 100.00
Name: Osser Len: 113 Check: 2604 Weight: 100.00
Name: Bare1 Len: 113 Check: 6970 Weight: 100.00
Name: Tnt1 Len: 113 Check: 6981 Weight: 100.00
Name: Ta1-3 Len: 113 Check: 5953 Weight: 100.00
Name: Tto1 Len: 113 Check: 9458 Weight: 100.00
Name: Evelknieve Len: 113 Check: 8785 Weight: 100.00
Name: Hopscotch Len: 113 Check: 8532 Weight: 100.00
Name: Sto-4 Len: 113 Check: 8140 Weight: 100.00
Name: Retrofit Len: 113 Check: 6649 Weight: 100.00
Name: MelmothAra Len: 113 Check: 6926 Weight: 100.00
Name: Melmothbra Len: 113 Check: 9363 Weight: 100.00
Name: Rire1 Len: 113 Check: 4927 Weight: 100.00
Name: Fourf Len: 113 Check: 1591 Weight: 100.00
Name: 1731 Len: 113 Check: 5135 Weight: 100.00
Name: Ty5 Len: 113 Check: 7305 Weight: 100.00
Name: Copia Len: 113 Check: 8420 Weight: 100.00
Name: Yokozuna Len: 113 Check: 2125 Weight: 100.00
Name: Ty4 Len: 113 Check: 1959 Weight: 100.00
Name: Lusen Len: 113 Check: 876 Weight: 100.00
Name: N3 Len: 113 Check: 8529 Weight: 100.00
Name: N4 Len: 113 Check: 3876 Weight: 100.00
Name: N2 Len: 113 Check: 4320 Weight: 100.00
Name: N7 Len: 113 Check: 1823 Weight: 100.00
Name: N6 Len: 113 Check: 1847 Weight: 100.00
Name: N9 Len: 113 Check: 3844 Weight: 100.00
Name: N12 Len: 113 Check: 8406 Weight: 100.00
Name: N11 Len: 113 Check: 1964 Weight: 100.00
Name: N16 Len: 113 Check: 527 Weight: 100.00
Name: N17 Len: 113 Check: 653 Weight: 100.00
Name: N15 Len: 113 Check: 647 Weight: 100.00
Name: N14 Len: 113 Check: 907 Weight: 100.00
Name: N20 Len: 113 Check: 4997 Weight: 100.00
Name: N21 Len: 113 Check: 189 Weight: 100.00
Name: N19 Len: 113 Check: 1284 Weight: 100.00
Name: N18 Len: 113 Check: 3518 Weight: 100.00
Name: N13 Len: 113 Check: 4247 Weight: 100.00
Name: N10 Len: 113 Check: 4279 Weight: 100.00
Name: N8 Len: 113 Check: 3780 Weight: 100.00
Name: N5 Len: 113 Check: 4070 Weight: 100.00
Name: N24 Len: 113 Check: 5962 Weight: 100.00
Name: N23 Len: 113 Check: 5607 Weight: 100.00
Name: N22 Len: 113 Check: 2558 Weight: 100.00
Name: N1 Len: 113 Check: 3560 Weight: 100.00
//
1 50
TNP2 LDTGTTNHMS GSR.AAFVKL DTA.VLG... ..TVRF.GDD PVARIEGHGT
Opie-2 VDSGCSRHMT GEA.KWFTSL TR..ASSDE. ..TITF.GDA SSGRVMAKGT
Endovir FDSGASRHMT GSQ.ANLNNY SS..VKES.. ..NVMF.GGG AKGRIKGKGD
ToRTL1 MDSGCSKHMI GDV.KNFLSL KT..LQGG.. ..GVSF.GDG KNGYILGVGK
Sire-1 LDSGCSRHMT GVK.EFLVNI E...PCSTS. ..YVTF.GDG SKGKITGMGK
Ty1 LDSGASRTLI RSA.HHIHSA SSN.P.D... ..INVVDAQK RNIPINAIGD
Ty2 IDSGASQTLV RSA.HYLHHA T...PNSEI. ..NIVD.AQK QDIPINAIGN
Osser LDSGAIYHVT PDA.RSLRDY K...PCDPI. ..PLKC.GGG EVHYAVGYGD
Bare1 LTSGLVMNLN NCYLVPALSM NI..ISGS.. ..CL.L.RDG YSFKSENNG.
Tnt1 VDTAASHHAT PVR.DLFCRY ....VAGDFG ..TVKM.GNT SYSKIAGIGD
Ta1-3 LDSGCTSHMS ARR.DWFCSF R...EDGGPT ..IL.L.GDD HSVKSQGQGS
Tto1 IDSGATIHAT PRR.ELFSSY ....TLGDFG ..RVKM.GNA NFSTVVGKGD
Evelknieve LDSGATHHLT SDL.NNLALH QP..YNGGE. ..EVTI.ADG SGLPISHSGS
Hopscotch TDTGATDHIT GDL.DRLTMH DK..YTGTD. ..QIIA.ANG TGMTISNIGN
Sto-4 IDSSATVHVA NSL.QGLRTS QRL.PKGRR. ..TIRV.ANG VEAAVEAIGD
Retrofit IDTGATDHIT GEL.EKLTTK EK..YNGGE. ..QIHT.ASG AGMDISHIGH
MelmothAra IDSGATHHVS HDR.SLFSS. ....LDTSVL S.AVNL.PTG PTVKISGVGT
Melmothbra IDSGATHHVC HDR.SMYTS. ....IDITTT S.NVNL.PNG MIVKISGVGI
Rire1 MDSGATVHIC ADR.SMFSS. ....FQGFNS A.PVLM.GNG VPAAVRGTGQ
Fourf MDSGANIHVC ADA.SMFTS. ....YQVGRS ..GALLMGNG SRAHVLGVGT
1731 LDSGATSHMC CDR.SVFTE. ....FEEHTE ..KISLAGNG .FLLAKGIGT
Ty5 FDTGCTSHMC HDR.SMFSS. ....FTRSSK KDFVRG.VGG .SIPIMGSGT
Copia LDSGASDHLI NDE.SLYTDS VELVPPL... ..KIAVAKQG EFIYATKRGI
Yokozuna IDSGASQNLV ID..SYEKYM SNIEYLETKT ..KIYV.ANG QYLFSSKKGI
Ty4 IDTGSGVNIT NDK.TLLHNY ED..SNRSTR ..FFGI.GKN SSVSVKGYGY
Lusen LDSGSPYHLT CDR.SLLHNY V...PAGAPK ..QIKW.GNN QLADVMGTGQ
N3 IDSGATHHAT PRRLELFSSY EKLETLGDFG ADTVKMAGNA SFSTVVGIGD
N4 MDSGATVHIC ADRLSMFTSY EKLEYQGSTS ADTVLMAGNG SSASVMGIGN
N2 IDSGATHHIT SDRLSMFTSY EKLEYQGSTS ADTVKMAGNG SSASVMGIGN
N7 LDSGATHHLI SDRLSMFTNY EKLEYNESTK ADKISVAGNG QFVFATKRGI
N6 LDSGATHHMT SDRLSMFTNY EKLEYNESTK ADKISVAGNG QFVFATGIGN
N9 LDSGATHHMT SDRLSMFHNY EKLEPNGSTK ADTIKVAGNN QSVSVMGIGN
N12 LDSGASQTLI RSALHHLHNA SSNEPNDEIK ADTIVVDAQK QNIPINAIGN
N11 LDSGATHHMT SDALSMLTNY ETLEPNDSIK ADTIKVAGNG QSVSVMGIGN
N16 LDSGCSRHMT GDRLANFVNL ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N17 LDSGCSRHMT GDRLKNFTNL ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N15 LDSGCSRHMT GDRLANFTNL ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N14 LDSGCSRHMT GDRLANFTNY ETLELNGSTK ADTVTFAGDG SSGRIMGIGT
N20 LDSGCTSHMS ARRLDWFCSF RTLEEDGGPT ADILKLAGDD HSVKSQGQGS
N21 IDSGATHHVS HDRLSMFTSY ETLELDTSTT SDTVNLAPNG QTVKISGVGT
N19 LDSGCTHHMS HDRLSMFTSY ETLELDGSTT ADTVKLAGNG QSVKIMGIGT
N18 LDSGCTHHMS HDRLSMFTSY ETLELNGSTK ADTVKVAGNG QSVRIMGIGT
N13 LDSGCTHHMT SDRLSMFTNY ETLELNGSTK ADTVKVAGNG QSVRIMGIGT
N10 LDSGATHHMT SDRLSMFTNY ETLEPNGSTK ADTIKVAGNG QSVSVMGIGN
N8 LDSGATHHMT SDRLSMFTNY EKLEPNGSTK ADTIKVAGNG QSVSVMGIGN
N5 LDSGATHHMT SDRLSMFTNY EKLEYNGSTK ADTIKVAGNG QSVSVMGIGN
N24 IDTGATDHIT GDLLDKLTTH EKLEYNGGEK ADQITAAANG SGMSISHIGN
N23 IDSGATHHIT SDLLNKLTTH EKLEYNGGEK ADQITVAANG SGMSISHIGN
N22 IDSGATHHIT SDLLSMFTSY EKLEYNGSTK ADTIKVAGNG SSASVMGIGN
N1 IDSGATHHIT SDRLSMFTSY EKLEYNGSTK ADTIKVAGNG SSASVMGIGN
51 100
TNP2 VVVCKN.GKL ..RSFSDVYY IPQLTTNIVS LGQ.LDE.AR YKVSINDGMM
Opie-2 IKVNDK.... ..FMLKDVAL VSKLKYNLLS VSQ.LCD.EN LEVRFKKDRS
Endovir LTETEK.... ..PHLTNVYF VEGLTANLIS VSQ.LCD.EG LTVSFNKVKC
ToRTL1 V......G.. ..RSLEDVYH VDGLKYSWLS VSQ.ICD.KG NEVKFTSEKC
Sire-1 L.VHD..G.. .......LRY V..KE.DRA. A.Q..CT.RQ DKMS.NEELK
Ty1 LQFHF..QDN .TKTSIKVLH TPNIAYDLLS LNE.LAA..V D.ITACFTKN
Ty2 LHFNF..GTK ..TSIK.ALH TPNIAYDLLS LSE.LAN.QN ITACFTRNTL
Osser LTYSFHIGPV .VIKIRNVYY VPGFKFRLLS LKQ.LTN.NG AQFSGSGTSM
Bare1 .......CS. ..ISMSNIFY GHASNVRRLF ILNLGSD.NT HIQNIETKRV
Tnt1 IITNV..GCT ..LVLKDVRH VPDLRMNLIS GIA.LDR.DG YESYFANQKW
Ta1-3 I.IETHGGTI ..IGLENVKY VPELRRNLIS TGT.LDK.RG IKHEGGDGKV
Tto1 V.LETMNGMK ..LLLRDVRH VPDMRLNLIS VDK.LDE.EG YCNTFHNGQV
Evelknieve ALLPTP.TRS ..LDLKDVLY VPDIQKNLIS VYR.MCN.TN GVSVEFFPAH
Hopscotch AIVPTS.SRS ..LHLRSVLH VPSTHKNLIS VHR.LTN.DN DVFIEFHSSH
Sto-4 IHLKLVNGFV ..LLLRDVLY VPSLRRNLIS VSR.LDD.QH IHCHFGDRQC
Retrofit TIVHTP.SRN ..IHLNNVLY VPQAKKNLIS ASQ.LAA.DN SAFLELHSKF
MelmothAra LKLND..D.. ..ILLKNVLF IPEFRLNLIS ISS.LTD.DI GSRVIFDKNS
Melmothbra VQLNE..H.. ..ITLHNVLY IPEFRLNLLS ISS.LTS.DI GSQVIFDVSS
Rire1 VYLKLTSGKT ..LVLKDVLY VPSMSRNLIS VSL.LCR.QG LKLVFESNKV
Fourf VILKFTSGKT ..VPLKSVQH VPSIKKNLVS ASM.LCR.DG YKVVL.ESNK
1731 VKLKTD.LCT ..LVLNNVLF VPDLNGNFMS VSR.AAQ.YK CFVNFGPHYA
Ty5 V..NI..GT. ..VQLNDVSY VPDLPVNLIS IWK.LCAKSN SSVTFTKEGV
Copia VRLRN..DHE ..ITLEDVLF CKEAAGNLMS VKR.LQE.AG MSIEFDKSGV
Yokozuna LNVKY...NN .LPIKIEALL VKGLSHNILS VKK.LLE.KG NSVRFHKNSV
Ty4 IKIKN..GHN NTDNKCLTYY VPEEESTIIS CYD.LAK.TT KMVLSRKYTR
Lusen LLLRTRDGES ..IWLRNVLH VPSSGLTLMS VDL.LVT.LG CSVTFGTDKA
N3 VILETMNGMT NTLVLKDVRH VPDMRLNLIS VDKLLDRKEG YSNTFGNGKV
N4 VILKLTSGKT NTLVLKDVLY VPSMRRNLIS VSLLLCRKQG YKVVFGNNKV
N2 VILKTTNGHT NTLVLKDVLY VPDMRRNLIS VSRLLARKQG YSVTFGNNKV
N7 VKLKTHNGHT NTLVLKDVLF VKDLSRNLMS VKRLLAEKQG SSVTFGKNKV
N6 VKLKTHNGHT NTLVLKDVLF VPDLSRNLMS VSRLLAEKQG SSVTFGKNKV
N9 VKLKTHNGHT NTISLKDVLY VPDLRRNLIS VSQLLANKQG SSVTFGKNKV
N12 LQFNFHNGTN NTTSIKKVLH TPNIAYDLLS LSELLANKQG STVTFSRNKL
N11 LKFNFHNGTT NTISIKDVLY VPDLRYNLLS LSQLLANKQG SSVTFSKNKV
N16 VKVNDKNGTT NTRSLKDVYY VPGLKYNLIS VSQLLCDKQG SKVSFNEEMC
N17 VKVNDKNGTT NTRSLKDVYY VPGLKYNLLS VSQLLCDKQG SEVSFNKEKC
N15 VKVNDKNGTT NTRSLKDVYY VPGLKYNLIS VSQLLCDKQG SKVSFNKEKC
N14 VKVNDKNGTT NTRSLKDVYY VPGLKYNLIS VSQLLCDKQG SKVSFNKEKC
N20 IKIETHGGTI NTIGLENVKY VPELRRNLIS TGTLLDKKRG IKHEGGDGKV
N21 VKLNDHNDTT NTISLKNVLY IPEFRLNLIS ISSLLTNKDI GSQVIFDENS
N19 VKLNTHNGTT NTISLKNVLY VPELRLNLIS ISSLLTNKQG SSQTFSDEKV
N18 VKLNTHNGTT NTISLKDVLY VPDLRLNLIS ISQLLCNKQG SSVTFSKEKV
N13 VKLNTHNGTT NTISLKDVLY VPDLRYNLIS VSQLLCNKQG SSVTFSKEKV
N10 VKLNTHNGTT NTISLKDVLY VPDLRYNLIS VSQLLANKQG SSVTFSKNKV
N8 VKLKTHNGHT NTISLKDVLY VPDLRRNLIS VSQLLANKQG SSVTFGKNKV
N5 VKLKTHNGHT NTLVLKDVLY VPDLRRNLIS VSRLLANKQG SSVTFGKNKV
N24 AIVPTPNSRS NTLHLKNVLY VPDTRKNLIS VSRLLANKDN SVFIEFHSKH
N23 AILPTPNSRS NTLHLKDVLY VPDTRKNLIS VSRLLANKDN SVFIEFHSKH
N22 VILKTTNGHT NTLVLKDVLY VPDMRRNLIS VSRLLANKQG SSVTFGNNKV
N1 VILKTTNGHT NTLVLKDVLY VPDMRRNLIS VSRLLANKQG SSVTFGNNKV
101 113
TNP2 QIREPDRQLL VK.
Opie-2 RVLDASESPV FDI
Endovir WATNERNQNT LTG
ToRTL1 TVVSLTTNKV ILT
Sire-1 .LQDP..... ...
Ty1 VLERSDGTVL API
Ty2 ERSDGTVLAP IVK
Osser DVWNSRERWS LYA
Bare1 RVNN.DSTMF LWH
Tnt1 RLTKGSLVIA KGV
Ta1-3 RYFKNQKTAL RGE
Tto1 KLTKGSLMVA RGT
Evelknieve FQVKDLSTGA RLL
Hopscotch FLIKDRQTKA VLL
Sto-4 VICFDNKVGL AIR
Retrofit FSIKDQVTRD VLL
MelmothAra CEIQDLIKGR MLG
Melmothbra CAIQDPTKGW TIG
Rire1 VLSKFGTFVG KSY
Fourf CVVSKHGTFV GKG
1731 DVIQEGERIL RVM
Ty5 TVKSPDDVIS TAG
Copia TISKNGLMVV KNS
Yokozuna SIAKGNNIIY GTM
Ty4 LGNKIIKIKT KIV
Lusen GTYLGPERGT AAH
N3 KLTKGSLMVA RGT
N4 VLTKGNEMVV RTT
N2 VLTKGNEMVV RTT
N7 VVTKGNEMVV RTT
N6 VVTKGNEMVV RTT
N9 VVTKGNEMVV RTT
N12 VLSKGNGMVL ITT
N11 VVTKGNEMVV ITT
N16 RVTDPNEQVV ITT
N17 RVTDPNEQVV ITT
N15 RVTDPNEQVV ITT
N14 RVTDPNEQVV ITT
N20 RYFKNQKTAL RGE
N21 CAIQDPTKGW TIG
N19 RVIKNQKMAL TTG
N18 RVTKPNEMVV TTG
N13 RVTKPNEMVV ITT
N10 VVTKGNEMVV ITT
N8 VVTKGNEMVV RTT
N5 VVTKGNEMVV RTT
N24 FLIKDQETRA VLL
N23 FLIKDQETGA RLL
N22 VLTKDNEMGV RTT
N1 VLTKGNEMVV RTT
Clustal
CLUSTAL X (1.81) multiple sequence alignment TNP2 LDTGTTNHMSGSR-AAFVKLDTA-VLG-----TVRF-GDDPVARIEGHGT Opie-2 VDSGCSRHMTGEA-KWFTSLTR--ASSDE---TITF-GDASSGRVMAKGT Endovir FDSGASRHMTGSQ-ANLNNYSS--VKES----NVMF-GGGAKGRIKGKGD ToRTL1 MDSGCSKHMIGDV-KNFLSLKT--LQGG----GVSF-GDGKNGYILGVGK Sire-1 LDSGCSRHMTGVK-EFLVNIE---PCSTS---YVTF-GDGSKGKITGMGK Ty1 LDSGASRTLIRSA-HHIHSASSN-P-D-----INVVDAQKRNIPINAIGD Ty2 IDSGASQTLVRSA-HYLHHAT---PNSEI---NIVD-AQKQDIPINAIGN Osser LDSGAIYHVTPDA-RSLRDYK---PCDPI---PLKC-GGGEVHYAVGYGD Bare1 LTSGLVMNLNNCYLVPALSMNI--ISGS----CL-L-RDGYSFKSENNG- Tnt1 VDTAASHHATPVR-DLFCRY----VAGDFG--TVKM-GNTSYSKIAGIGD Ta1-3 LDSGCTSHMSARR-DWFCSFR---EDGGPT--IL-L-GDDHSVKSQGQGS Tto1 IDSGATIHATPRR-ELFSSY----TLGDFG--RVKM-GNANFSTVVGKGD Evelknieve LDSGATHHLTSDL-NNLALHQP--YNGGE---EVTI-ADGSGLPISHSGS Hopscotch TDTGATDHITGDL-DRLTMHDK--YTGTD---QIIA-ANGTGMTISNIGN Sto-4 IDSSATVHVANSL-QGLRTSQRL-PKGRR---TIRV-ANGVEAAVEAIGD Retrofit IDTGATDHITGEL-EKLTTKEK--YNGGE---QIHT-ASGAGMDISHIGH MelmothAra IDSGATHHVSHDR-SLFSS-----LDTSVLS-AVNL-PTGPTVKISGVGT Melmothbra IDSGATHHVCHDR-SMYTS-----IDITTTS-NVNL-PNGMIVKISGVGI Rire1 MDSGATVHICADR-SMFSS-----FQGFNSA-PVLM-GNGVPAAVRGTGQ Fourf MDSGANIHVCADA-SMFTS-----YQVGRS--GALLMGNGSRAHVLGVGT 1731 LDSGATSHMCCDR-SVFTE-----FEEHTE--KISLAGNG-FLLAKGIGT Ty5 FDTGCTSHMCHDR-SMFSS-----FTRSSKKDFVRG-VGG-SIPIMGSGT Copia LDSGASDHLINDE-SLYTDSVELVPPL-----KIAVAKQGEFIYATKRGI Yokozuna IDSGASQNLVID--SYEKYMSNIEYLETKT--KIYV-ANGQYLFSSKKGI Ty4 IDTGSGVNITNDK-TLLHNYED--SNRSTR--FFGI-GKNSSVSVKGYGY Lusen LDSGSPYHLTCDR-SLLHNYV---PAGAPK--QIKW-GNNQLADVMGTGQ N3 IDSGATHHATPRRLELFSSYEKLETLGDFGADTVKMAGNASFSTVVGIGD N4 MDSGATVHICADRLSMFTSYEKLEYQGSTSADTVLMAGNGSSASVMGIGN N2 IDSGATHHITSDRLSMFTSYEKLEYQGSTSADTVKMAGNGSSASVMGIGN N7 LDSGATHHLISDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATKRGI N6 LDSGATHHMTSDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATGIGN N9 LDSGATHHMTSDRLSMFHNYEKLEPNGSTKADTIKVAGNNQSVSVMGIGN N12 LDSGASQTLIRSALHHLHNASSNEPNDEIKADTIVVDAQKQNIPINAIGN N11 LDSGATHHMTSDALSMLTNYETLEPNDSIKADTIKVAGNGQSVSVMGIGN N16 LDSGCSRHMTGDRLANFVNLETLELNGSTKADTVTFAGDGSSGRIMGIGT N17 LDSGCSRHMTGDRLKNFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT N15 LDSGCSRHMTGDRLANFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT N14 LDSGCSRHMTGDRLANFTNYETLELNGSTKADTVTFAGDGSSGRIMGIGT N20 LDSGCTSHMSARRLDWFCSFRTLEEDGGPTADILKLAGDDHSVKSQGQGS N21 IDSGATHHVSHDRLSMFTSYETLELDTSTTSDTVNLAPNGQTVKISGVGT N19 LDSGCTHHMSHDRLSMFTSYETLELDGSTTADTVKLAGNGQSVKIMGIGT N18 LDSGCTHHMSHDRLSMFTSYETLELNGSTKADTVKVAGNGQSVRIMGIGT N13 LDSGCTHHMTSDRLSMFTNYETLELNGSTKADTVKVAGNGQSVRIMGIGT N10 LDSGATHHMTSDRLSMFTNYETLEPNGSTKADTIKVAGNGQSVSVMGIGN N8 LDSGATHHMTSDRLSMFTNYEKLEPNGSTKADTIKVAGNGQSVSVMGIGN N5 LDSGATHHMTSDRLSMFTNYEKLEYNGSTKADTIKVAGNGQSVSVMGIGN N24 IDTGATDHITGDLLDKLTTHEKLEYNGGEKADQITAAANGSGMSISHIGN N23 IDSGATHHITSDLLNKLTTHEKLEYNGGEKADQITVAANGSGMSISHIGN N22 IDSGATHHITSDLLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN N1 IDSGATHHITSDRLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN TNP2 VVVCKN-GKL--RSFSDVYYIPQLTTNIVSLGQ-LDE-ARYKVSINDGMM Opie-2 IKVNDK------FMLKDVALVSKLKYNLLSVSQ-LCD-ENLEVRFKKDRS Endovir LTETEK------PHLTNVYFVEGLTANLISVSQ-LCD-EGLTVSFNKVKC ToRTL1 V------G----RSLEDVYHVDGLKYSWLSVSQ-ICD-KGNEVKFTSEKC Sire-1 L-VHD--G---------LRYV--KE-DRA-A-Q--CT-RQDKMS-NEELK Ty1 LQFHF--QDN-TKTSIKVLHTPNIAYDLLSLNE-LAA--VD-ITACFTKN Ty2 LHFNF--GTK--TSIK-ALHTPNIAYDLLSLSE-LAN-QNITACFTRNTL Osser LTYSFHIGPV-VIKIRNVYYVPGFKFRLLSLKQ-LTN-NGAQFSGSGTSM Bare1 -------CS---ISMSNIFYGHASNVRRLFILNLGSD-NTHIQNIETKRV Tnt1 IITNV--GCT--LVLKDVRHVPDLRMNLISGIA-LDR-DGYESYFANQKW Ta1-3 I-IETHGGTI--IGLENVKYVPELRRNLISTGT-LDK-RGIKHEGGDGKV Tto1 V-LETMNGMK--LLLRDVRHVPDMRLNLISVDK-LDE-EGYCNTFHNGQV Evelknieve ALLPTP-TRS--LDLKDVLYVPDIQKNLISVYR-MCN-TNGVSVEFFPAH Hopscotch AIVPTS-SRS--LHLRSVLHVPSTHKNLISVHR-LTN-DNDVFIEFHSSH Sto-4 IHLKLVNGFV--LLLRDVLYVPSLRRNLISVSR-LDD-QHIHCHFGDRQC Retrofit TIVHTP-SRN--IHLNNVLYVPQAKKNLISASQ-LAA-DNSAFLELHSKF MelmothAra LKLND--D----ILLKNVLFIPEFRLNLISISS-LTD-DIGSRVIFDKNS Melmothbra VQLNE--H----ITLHNVLYIPEFRLNLLSISS-LTS-DIGSQVIFDVSS Rire1 VYLKLTSGKT--LVLKDVLYVPSMSRNLISVSL-LCR-QGLKLVFESNKV Fourf VILKFTSGKT--VPLKSVQHVPSIKKNLVSASM-LCR-DGYKVVL-ESNK 1731 VKLKTD-LCT--LVLNNVLFVPDLNGNFMSVSR-AAQ-YKCFVNFGPHYA Ty5 V--NI--GT---VQLNDVSYVPDLPVNLISIWK-LCAKSNSSVTFTKEGV Copia VRLRN--DHE--ITLEDVLFCKEAAGNLMSVKR-LQE-AGMSIEFDKSGV Yokozuna LNVKY---NN-LPIKIEALLVKGLSHNILSVKK-LLE-KGNSVRFHKNSV Ty4 IKIKN--GHNNTDNKCLTYYVPEEESTIISCYD-LAK-TTKMVLSRKYTR Lusen LLLRTRDGES--IWLRNVLHVPSSGLTLMSVDL-LVT-LGCSVTFGTDKA N3 VILETMNGMTNTLVLKDVRHVPDMRLNLISVDKLLDRKEGYSNTFGNGKV N4 VILKLTSGKTNTLVLKDVLYVPSMRRNLISVSLLLCRKQGYKVVFGNNKV N2 VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLARKQGYSVTFGNNKV N7 VKLKTHNGHTNTLVLKDVLFVKDLSRNLMSVKRLLAEKQGSSVTFGKNKV N6 VKLKTHNGHTNTLVLKDVLFVPDLSRNLMSVSRLLAEKQGSSVTFGKNKV N9 VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV N12 LQFNFHNGTNNTTSIKKVLHTPNIAYDLLSLSELLANKQGSTVTFSRNKL N11 LKFNFHNGTTNTISIKDVLYVPDLRYNLLSLSQLLANKQGSSVTFSKNKV N16 VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNEEMC N17 VKVNDKNGTTNTRSLKDVYYVPGLKYNLLSVSQLLCDKQGSEVSFNKEKC N15 VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC N14 VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC N20 IKIETHGGTINTIGLENVKYVPELRRNLISTGTLLDKKRGIKHEGGDGKV N21 VKLNDHNDTTNTISLKNVLYIPEFRLNLISISSLLTNKDIGSQVIFDENS N19 VKLNTHNGTTNTISLKNVLYVPELRLNLISISSLLTNKQGSSQTFSDEKV N18 VKLNTHNGTTNTISLKDVLYVPDLRLNLISISQLLCNKQGSSVTFSKEKV N13 VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLCNKQGSSVTFSKEKV N10 VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLANKQGSSVTFSKNKV N8 VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV N5 VKLKTHNGHTNTLVLKDVLYVPDLRRNLISVSRLLANKQGSSVTFGKNKV N24 AIVPTPNSRSNTLHLKNVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH N23 AILPTPNSRSNTLHLKDVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH N22 VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV N1 VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV TNP2 QIREPDRQLLVK- Opie-2 RVLDASESPVFDI Endovir WATNERNQNTLTG ToRTL1 TVVSLTTNKVILT Sire-1 -LQDP-------- Ty1 VLERSDGTVLAPI Ty2 ERSDGTVLAPIVK Osser DVWNSRERWSLYA Bare1 RVNN-DSTMFLWH Tnt1 RLTKGSLVIAKGV Ta1-3 RYFKNQKTALRGE Tto1 KLTKGSLMVARGT Evelknieve FQVKDLSTGARLL Hopscotch FLIKDRQTKAVLL Sto-4 VICFDNKVGLAIR Retrofit FSIKDQVTRDVLL MelmothAra CEIQDLIKGRMLG Melmothbra CAIQDPTKGWTIG Rire1 VLSKFGTFVGKSY Fourf CVVSKHGTFVGKG 1731 DVIQEGERILRVM Ty5 TVKSPDDVISTAG Copia TISKNGLMVVKNS Yokozuna SIAKGNNIIYGTM Ty4 LGNKIIKIKTKIV Lusen GTYLGPERGTAAH N3 KLTKGSLMVARGT N4 VLTKGNEMVVRTT N2 VLTKGNEMVVRTT N7 VVTKGNEMVVRTT N6 VVTKGNEMVVRTT N9 VVTKGNEMVVRTT N12 VLSKGNGMVLITT N11 VVTKGNEMVVITT N16 RVTDPNEQVVITT N17 RVTDPNEQVVITT N15 RVTDPNEQVVITT N14 RVTDPNEQVVITT N20 RYFKNQKTALRGE N21 CAIQDPTKGWTIG N19 RVIKNQKMALTTG N18 RVTKPNEMVVTTG N13 RVTKPNEMVVITT N10 VVTKGNEMVVITT N8 VVTKGNEMVVRTT N5 VVTKGNEMVVRTT N24 FLIKDQETRAVLL N23 FLIKDQETGARLL N22 VLTKDNEMGVRTT N1 VLTKGNEMVVRTT
Stokholm
# STOCKHOLM 1.0 TNP2 LDTGTTNHMSGSR.AAFVKLDTA.VLG.....TVRF.GDDPVARIEGHGT Opie-2 VDSGCSRHMTGEA.KWFTSLTR..ASSDE...TITF.GDASSGRVMAKGT Endovir FDSGASRHMTGSQ.ANLNNYSS..VKES....NVMF.GGGAKGRIKGKGD ToRTL1 MDSGCSKHMIGDV.KNFLSLKT..LQGG....GVSF.GDGKNGYILGVGK Sire-1 LDSGCSRHMTGVK.EFLVNIE...PCSTS...YVTF.GDGSKGKITGMGK Ty1 LDSGASRTLIRSA.HHIHSASSN.P.D.....INVVDAQKRNIPINAIGD Ty2 IDSGASQTLVRSA.HYLHHAT...PNSEI...NIVD.AQKQDIPINAIGN Osser LDSGAIYHVTPDA.RSLRDYK...PCDPI...PLKC.GGGEVHYAVGYGD Bare1 LTSGLVMNLNNCYLVPALSMNI..ISGS....CL.L.RDGYSFKSENNG. Tnt1 VDTAASHHATPVR.DLFCRY....VAGDFG..TVKM.GNTSYSKIAGIGD Ta1-3 LDSGCTSHMSARR.DWFCSFR...EDGGPT..IL.L.GDDHSVKSQGQGS Tto1 IDSGATIHATPRR.ELFSSY....TLGDFG..RVKM.GNANFSTVVGKGD Evelknieve LDSGATHHLTSDL.NNLALHQP..YNGGE...EVTI.ADGSGLPISHSGS Hopscotch TDTGATDHITGDL.DRLTMHDK..YTGTD...QIIA.ANGTGMTISNIGN Sto-4 IDSSATVHVANSL.QGLRTSQRL.PKGRR...TIRV.ANGVEAAVEAIGD Retrofit IDTGATDHITGEL.EKLTTKEK..YNGGE...QIHT.ASGAGMDISHIGH MelmothAra IDSGATHHVSHDR.SLFSS.....LDTSVLS.AVNL.PTGPTVKISGVGT Melmothbra IDSGATHHVCHDR.SMYTS.....IDITTTS.NVNL.PNGMIVKISGVGI Rire1 MDSGATVHICADR.SMFSS.....FQGFNSA.PVLM.GNGVPAAVRGTGQ Fourf MDSGANIHVCADA.SMFTS.....YQVGRS..GALLMGNGSRAHVLGVGT 1731 LDSGATSHMCCDR.SVFTE.....FEEHTE..KISLAGNG.FLLAKGIGT Ty5 FDTGCTSHMCHDR.SMFSS.....FTRSSKKDFVRG.VGG.SIPIMGSGT Copia LDSGASDHLINDE.SLYTDSVELVPPL.....KIAVAKQGEFIYATKRGI Yokozuna IDSGASQNLVID..SYEKYMSNIEYLETKT..KIYV.ANGQYLFSSKKGI Ty4 IDTGSGVNITNDK.TLLHNYED..SNRSTR..FFGI.GKNSSVSVKGYGY Lusen LDSGSPYHLTCDR.SLLHNYV...PAGAPK..QIKW.GNNQLADVMGTGQ N3 IDSGATHHATPRRLELFSSYEKLETLGDFGADTVKMAGNASFSTVVGIGD N4 MDSGATVHICADRLSMFTSYEKLEYQGSTSADTVLMAGNGSSASVMGIGN N2 IDSGATHHITSDRLSMFTSYEKLEYQGSTSADTVKMAGNGSSASVMGIGN N7 LDSGATHHLISDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATKRGI N6 LDSGATHHMTSDRLSMFTNYEKLEYNESTKADKISVAGNGQFVFATGIGN N9 LDSGATHHMTSDRLSMFHNYEKLEPNGSTKADTIKVAGNNQSVSVMGIGN N12 LDSGASQTLIRSALHHLHNASSNEPNDEIKADTIVVDAQKQNIPINAIGN N11 LDSGATHHMTSDALSMLTNYETLEPNDSIKADTIKVAGNGQSVSVMGIGN N16 LDSGCSRHMTGDRLANFVNLETLELNGSTKADTVTFAGDGSSGRIMGIGT N17 LDSGCSRHMTGDRLKNFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT N15 LDSGCSRHMTGDRLANFTNLETLELNGSTKADTVTFAGDGSSGRIMGIGT N14 LDSGCSRHMTGDRLANFTNYETLELNGSTKADTVTFAGDGSSGRIMGIGT N20 LDSGCTSHMSARRLDWFCSFRTLEEDGGPTADILKLAGDDHSVKSQGQGS N21 IDSGATHHVSHDRLSMFTSYETLELDTSTTSDTVNLAPNGQTVKISGVGT N19 LDSGCTHHMSHDRLSMFTSYETLELDGSTTADTVKLAGNGQSVKIMGIGT N18 LDSGCTHHMSHDRLSMFTSYETLELNGSTKADTVKVAGNGQSVRIMGIGT N13 LDSGCTHHMTSDRLSMFTNYETLELNGSTKADTVKVAGNGQSVRIMGIGT N10 LDSGATHHMTSDRLSMFTNYETLEPNGSTKADTIKVAGNGQSVSVMGIGN N8 LDSGATHHMTSDRLSMFTNYEKLEPNGSTKADTIKVAGNGQSVSVMGIGN N5 LDSGATHHMTSDRLSMFTNYEKLEYNGSTKADTIKVAGNGQSVSVMGIGN N24 IDTGATDHITGDLLDKLTTHEKLEYNGGEKADQITAAANGSGMSISHIGN N23 IDSGATHHITSDLLNKLTTHEKLEYNGGEKADQITVAANGSGMSISHIGN N22 IDSGATHHITSDLLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN N1 IDSGATHHITSDRLSMFTSYEKLEYNGSTKADTIKVAGNGSSASVMGIGN TNP2 VVVCKN.GKL..RSFSDVYYIPQLTTNIVSLGQ.LDE.ARYKVSINDGMM Opie-2 IKVNDK......FMLKDVALVSKLKYNLLSVSQ.LCD.ENLEVRFKKDRS Endovir LTETEK......PHLTNVYFVEGLTANLISVSQ.LCD.EGLTVSFNKVKC ToRTL1 V......G....RSLEDVYHVDGLKYSWLSVSQ.ICD.KGNEVKFTSEKC Sire-1 L.VHD..G.........LRYV..KE.DRA.A.Q..CT.RQDKMS.NEELK Ty1 LQFHF..QDN.TKTSIKVLHTPNIAYDLLSLNE.LAA..VD.ITACFTKN Ty2 LHFNF..GTK..TSIK.ALHTPNIAYDLLSLSE.LAN.QNITACFTRNTL Osser LTYSFHIGPV.VIKIRNVYYVPGFKFRLLSLKQ.LTN.NGAQFSGSGTSM Bare1 .......CS...ISMSNIFYGHASNVRRLFILNLGSD.NTHIQNIETKRV Tnt1 IITNV..GCT..LVLKDVRHVPDLRMNLISGIA.LDR.DGYESYFANQKW Ta1-3 I.IETHGGTI..IGLENVKYVPELRRNLISTGT.LDK.RGIKHEGGDGKV Tto1 V.LETMNGMK..LLLRDVRHVPDMRLNLISVDK.LDE.EGYCNTFHNGQV Evelknieve ALLPTP.TRS..LDLKDVLYVPDIQKNLISVYR.MCN.TNGVSVEFFPAH Hopscotch AIVPTS.SRS..LHLRSVLHVPSTHKNLISVHR.LTN.DNDVFIEFHSSH Sto-4 IHLKLVNGFV..LLLRDVLYVPSLRRNLISVSR.LDD.QHIHCHFGDRQC Retrofit TIVHTP.SRN..IHLNNVLYVPQAKKNLISASQ.LAA.DNSAFLELHSKF MelmothAra LKLND..D....ILLKNVLFIPEFRLNLISISS.LTD.DIGSRVIFDKNS Melmothbra VQLNE..H....ITLHNVLYIPEFRLNLLSISS.LTS.DIGSQVIFDVSS Rire1 VYLKLTSGKT..LVLKDVLYVPSMSRNLISVSL.LCR.QGLKLVFESNKV Fourf VILKFTSGKT..VPLKSVQHVPSIKKNLVSASM.LCR.DGYKVVL.ESNK 1731 VKLKTD.LCT..LVLNNVLFVPDLNGNFMSVSR.AAQ.YKCFVNFGPHYA Ty5 V..NI..GT...VQLNDVSYVPDLPVNLISIWK.LCAKSNSSVTFTKEGV Copia VRLRN..DHE..ITLEDVLFCKEAAGNLMSVKR.LQE.AGMSIEFDKSGV Yokozuna LNVKY...NN.LPIKIEALLVKGLSHNILSVKK.LLE.KGNSVRFHKNSV Ty4 IKIKN..GHNNTDNKCLTYYVPEEESTIISCYD.LAK.TTKMVLSRKYTR Lusen LLLRTRDGES..IWLRNVLHVPSSGLTLMSVDL.LVT.LGCSVTFGTDKA N3 VILETMNGMTNTLVLKDVRHVPDMRLNLISVDKLLDRKEGYSNTFGNGKV N4 VILKLTSGKTNTLVLKDVLYVPSMRRNLISVSLLLCRKQGYKVVFGNNKV N2 VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLARKQGYSVTFGNNKV N7 VKLKTHNGHTNTLVLKDVLFVKDLSRNLMSVKRLLAEKQGSSVTFGKNKV N6 VKLKTHNGHTNTLVLKDVLFVPDLSRNLMSVSRLLAEKQGSSVTFGKNKV N9 VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV N12 LQFNFHNGTNNTTSIKKVLHTPNIAYDLLSLSELLANKQGSTVTFSRNKL N11 LKFNFHNGTTNTISIKDVLYVPDLRYNLLSLSQLLANKQGSSVTFSKNKV N16 VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNEEMC N17 VKVNDKNGTTNTRSLKDVYYVPGLKYNLLSVSQLLCDKQGSEVSFNKEKC N15 VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC N14 VKVNDKNGTTNTRSLKDVYYVPGLKYNLISVSQLLCDKQGSKVSFNKEKC N20 IKIETHGGTINTIGLENVKYVPELRRNLISTGTLLDKKRGIKHEGGDGKV N21 VKLNDHNDTTNTISLKNVLYIPEFRLNLISISSLLTNKDIGSQVIFDENS N19 VKLNTHNGTTNTISLKNVLYVPELRLNLISISSLLTNKQGSSQTFSDEKV N18 VKLNTHNGTTNTISLKDVLYVPDLRLNLISISQLLCNKQGSSVTFSKEKV N13 VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLCNKQGSSVTFSKEKV N10 VKLNTHNGTTNTISLKDVLYVPDLRYNLISVSQLLANKQGSSVTFSKNKV N8 VKLKTHNGHTNTISLKDVLYVPDLRRNLISVSQLLANKQGSSVTFGKNKV N5 VKLKTHNGHTNTLVLKDVLYVPDLRRNLISVSRLLANKQGSSVTFGKNKV N24 AIVPTPNSRSNTLHLKNVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH N23 AILPTPNSRSNTLHLKDVLYVPDTRKNLISVSRLLANKDNSVFIEFHSKH N22 VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV N1 VILKTTNGHTNTLVLKDVLYVPDMRRNLISVSRLLANKQGSSVTFGNNKV TNP2 QIREPDRQLLVK. Opie-2 RVLDASESPVFDI Endovir WATNERNQNTLTG ToRTL1 TVVSLTTNKVILT Sire-1 .LQDP........ Ty1 VLERSDGTVLAPI Ty2 ERSDGTVLAPIVK Osser DVWNSRERWSLYA Bare1 RVNN.DSTMFLWH Tnt1 RLTKGSLVIAKGV Ta1-3 RYFKNQKTALRGE Tto1 KLTKGSLMVARGT Evelknieve FQVKDLSTGARLL Hopscotch FLIKDRQTKAVLL Sto-4 VICFDNKVGLAIR Retrofit FSIKDQVTRDVLL MelmothAra CEIQDLIKGRMLG Melmothbra CAIQDPTKGWTIG Rire1 VLSKFGTFVGKSY Fourf CVVSKHGTFVGKG 1731 DVIQEGERILRVM Ty5 TVKSPDDVISTAG Copia TISKNGLMVVKNS Yokozuna SIAKGNNIIYGTM Ty4 LGNKIIKIKTKIV Lusen GTYLGPERGTAAH N3 KLTKGSLMVARGT N4 VLTKGNEMVVRTT N2 VLTKGNEMVVRTT N7 VVTKGNEMVVRTT N6 VVTKGNEMVVRTT N9 VVTKGNEMVVRTT N12 VLSKGNGMVLITT N11 VVTKGNEMVVITT N16 RVTDPNEQVVITT N17 RVTDPNEQVVITT N15 RVTDPNEQVVITT N14 RVTDPNEQVVITT N20 RYFKNQKTALRGE N21 CAIQDPTKGWTIG N19 RVIKNQKMALTTG N18 RVTKPNEMVVTTG N13 RVTKPNEMVVITT N10 VVTKGNEMVVITT N8 VVTKGNEMVVRTT N5 VVTKGNEMVVRTT N24 FLIKDQETRAVLL N23 FLIKDQETGARLL N22 VLTKDNEMGVRTT N1 VLTKGNEMVVRTT //