DescriptionCoDi4.5 is a Ty1/Copia LTR retrotransposon described in the genome of the marine algae phytoplankton Thalassiosira pseudonana (Maumus et al. 2009; Bowler et al. 2008). This element belongs to CoDi-I clade, within Branch 1 of the Ty1/Copia family (Llorens et al. 2009). Interestingly, CoDi-I represents the first described set of Ty1/Copia elements carrying a putative chromodomain at the C-terminus of the pol-INT domain (Llorens et al. 2009) similarly to Ty3/Gypsy chromoviruses (Marin and Lloréns 2000), which use this feature for chromatin integration (Gao et al. 2008). CoDi4.5 genome, of 6715 bp in size, includes 235-bp LTRs that flank a long Open Reading Frame (ORF), interrupted by one stop codon, displaying the gag and pol typical structure of the Ty1/Copia LTR retrotransposons (gag, protease, integrase, reverse transcriptase and ribonuclease H, for more details, see Maumus et al. 2009). Structure
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Llorens, C., Futami, R., Covelli, L., Dominguez-Escriba, L., Viu, J.M., Tamarit, D., Aguilar-Rodriguez, J. Vicente-Ripolles, M., Fuster, G., Bernet, G.P., Maumus, F., Munoz-Pomer, A., Sempere, J.M., LaTorre, A., Moya, A. (2011) The Gypsy Database (GyDB) of Mobile Genetic Elements: Release 2.0 Nucleic Acids Research (NARESE) 39 (suppl 1): D70-D74 doi: 10.1093/nar/gkq1061