Element:Moose

Description Moose is a LTR retrotransposon described in the genome of the malaria transmitting mosquito Anopheles gambiae (Biessmann et al. 1999). Moose belongs to the Bel clade (Copeland et al. 2005) within Branch 1 of the Bel/Pao family (Llorens et al. 2009). The genome of Moose is about of 6 Kb in size (5983 bp in lenght). The internal coding region, flanked by LTRs of 265 nt, displays three ORFs encoding for gag and pol polyproteins. The gag contains the three putative Cys-motifs characteristic of the gag associated nucleocapsid domain, while pol clearly presents the protease, the reverse transcriptase, the RNase H and the integrase domains (Biessmann et al. 1999). Structure Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean: MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein Related literature Mobile DNA II. (Craig et al. 2002)

Genbank accession: 3347855 Clade: Bel Cluster or genus: Undetermined Branch or class: Branch 1 Family: Bel/Pao System: LTR retroelements Host: Explore the Tree Life Project Anopheles gambiae Courtesy of James D. Gathany, CDC Browse all elements