Element:Mabel

Description Mabel is a LTR retrotransposon found in the genome of the nematode parasite Brugia malayi (Llorens et al. 2009). Its name is an acronym derived from "Brugia malayi Bel/Pao element". Mabel belongs to the Tas clade (Copeland et al. 2005) within Branch 1 of the Bel/Pao family (Llorens et al. 2009). The genome of Mabel is 5.4 Kb in size (5436 bp long) and presents a single long polyprotein of 1811 amino acids containing both gag and pol associated domains (Llorens et al. 2009). No LTRs have been yet identified for this element. Structure Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean: MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein Related literature Mobile DNA II. (Craig et al. 2002)

Genbank accession: 170588120 Clade: Tas Cluster or genus: Undetermined Branch or class: Branch 1 Family: Bel/Pao System: LTR retroelements Host: Explore the Tree Life Project Brugia malayi Cortesy of CDC-DPDx Browse all elements