Element:GalEa1

Revision as of 09:23, 11 March 2010 by imported>Lcovelli
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Description

GalEa1, characterized in the genome of the squat lobster (Eumunida annulosa), represents the first Ty1/Copia-like LTR retrotransposon described in Crustacea (Terrat et al. 2008). It belongs to GalEA clade a Ty1/Copia lineage specifically found in marin animals (Terrat et al. 2008).

The genome of GalEa1 is 4669 bp in size, including LTRs of 124 bp long. The LTRs bounded internal region contains a Primer Binding Site (PBS) complementary to a tRNAMet, a single large Open Reading Frame (ORF) (which harbors a stop codon at position 1.516 and a frameshift at position 1.979) and a Polypurine Tract (PPT) adjacent to its 3’LTR. The translated region displays the typical gag and pol polyprotein domains of Ty1/Copia LTR retrotransposons: gag, protease, integrase, reverse transcriptase and ribonuclease H (Terrat et al. 2008).

Structure

GalEa1.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession: 156600407
Clade: GalEA
Cluster or genus: Undetermined
Branch or class: Branch 1
Family: Ty1/Copia
System: LTR retroelements
Host:
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Eumunida spp.jpg
Eumunida spp
Cortesy of the Biological library (BioLib), Dr.Tamara Frank author
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Llorens, C., Futami, R., Covelli, L., Dominguez-Escriba, L., Viu, J.M., Tamarit, D., Aguilar-Rodriguez, J. Vicente-Ripolles, M., Fuster, G., Bernet, G.P., Maumus, F., Munoz-Pomer, A., Sempere, J.M., LaTorre, A., Moya, A. (2011) The Gypsy Database (GyDB) of Mobile Genetic Elements: Release 2.0 Nucleic Acids Research (NARESE) 39 (suppl 1): D70-D74 doi: 10.1093/nar/gkq1061

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