Element:Tft2

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Description

Tit for tat type 2 (Tft2) is a retrotransposon described along with Tft1 in the genome of Arabidopsis thaliana (Marín and Lloréns 2000). This element belongs to a lineage of plant LTR retrotransposons (Tat), sibling of other lineage of putative plant endogenous retroviruses (Athila), providing evidence of a shared ancestral lineage originally described as class A by Wright and Voytas (1998). Tft2 has several subtypes, the Tft2 sequence available in the genbank accession AC018928 is taken as a representative. This clone is 13.2 Kb in size including LTRs of 0.5Kb. The internal region of this element displays a Primer Binding Site (PBS) complementary to a tRNA Arg, four Open Reading Frames (ORFs) for gag, pro, and pol genes, and a Polypurine Tract (PPT) adjacent to the 3´LTR (Marín and Lloréns 2000). As other Tat-like elements, Tft2 displays downstream to the integrase domain an untranslated region of 8 Kb from which little is known.

Structure

Tft2.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession: AC018928 (nuc. 11471-24670)
Clade: Tat
Cluster or genus: Athila/Tat
Branch or class: Branch 2
Family: Ty3/Gypsy
System: LTR retroelements
Host:
Explore the Tree Life Project
Arabidopsis thaliana.gif
Arabidopsis thaliana
Photo: www.knoch1.de
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Welcome to the Gypsy Database (GyDB) an open editable database about the evolutionary relationship of viruses, mobile genetic elements (MGEs) and the genomic repeats where we invite all authors to contribute with their knowledge to improve and expand the topics.
Cite this project:

Llorens, C., Futami, R., Covelli, L., Dominguez-Escriba, L., Viu, J.M., Tamarit, D., Aguilar-Rodriguez, J. Vicente-Ripolles, M., Fuster, G., Bernet, G.P., Maumus, F., Munoz-Pomer, A., Sempere, J.M., LaTorre, A., Moya, A. (2011) The Gypsy Database (GyDB) of Mobile Genetic Elements: Release 2.0 Nucleic Acids Research (NARESE) 39 (suppl 1): D70-D74 doi: 10.1093/nar/gkq1061

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