Element:Mdg3

Description Mdg3 is a LTR retrotransposon described in the genome of Drosophila melanogaster (Ilyin et al. 1985). Mdg3 belongs, along with other Ty3/Gypsy LTR retrotransposons, to Micropia/mdg3 clade (Malik and Eickbush 1999). The genomic structure of mdg3 is 5.5Kb in size including LTRs with a size oscillating between 267 and 293 nt (depending on the mdg3 variant). The internal region of this element displays a Primer Binding Site (PBS), a single Open Reading Frame (ORF) that codifies for a gag-pol polyprotein, and a Polypurine Tract (PPT) adjacent to the 3´LTR (Ilyin et al. 1985; Dzhumgaliev et al. 1986; Avedisov and Il'in,Iu. 1995). Structure Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean: MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein Related literature Mobile DNA II. (Craig et al. 2002)

Genbank accession: X95908 Clade: Micropia/Mdg3 Cluster or genus: Undetermined Branch or class: Branch 2 Family: Ty3/Gypsy System: LTR retroelements Host: Explore the Tree Life Project Drosophila melanogaster Image, courtesy of Andreas Trepte, Max-Planck Institute for Molecular Genetics Browse all elements