Element:Cyclops-2

Description Cyclops is a LTR retroelement described in Pisum sativum (Chavanne et al 1998). Cyclops belongs to a lineage of possible retroviruses in plants (Wright and Voytas 2002), which is also related to other lineage (Tat) of plant LTR retrotransposons, providing evidence of a shared ancestral lineage originally described as class A by Wright and Voytas (1998). The figure below describes the Cyclops consensus. However, this elements has several subtypes; Subtype 2 is taken as representative. The genome of Cyclops-2 is 12.2 Kb in size, including LTRs of 1.5 Kb. Its internal region displays a Primer Binding Site (PBS) complementary to a tRNAAsp, three Open Reading Frames (ORFs) for gag, pol, and env genes, and two Polypurine Tracts, PPT1 and PPT2 adjacent to the 3´LTR (Chavanne et al 1998; Wright and Voytas 1998; 2002). Structure Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean: MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein Related literature Mobile DNA II. (Craig et al. 2002)

Genbank accession: AJ000640 Clade: Athila Cluster or genus: Athila/Tat Branch or class: Branch 2 Family: Ty3/Gypsy System: LTR retroelements Host: Explore the Tree Life Project Pisum sativum Courtesy of Renee Comet, National Cancer Institute Browse all elements