Description
Ted is a retrovirus described as a sequence inserted in the Autographa californica nucleo polyhedrovirus (AcMNPV) (Miller and Miller 1982). Ted belongs to 17.6 clade of genus Errantiviridae (Boeke et al. 1999; Pringle 1998; 1999; Hull 1999), a lineage of fly-retroviruses and LTR retrotransposons closely related to 412/mdg1 clade (Tubio, Naveira and Costas 2005). The genomic structure of Ted is 7.5 Kb in size including LTRs of 273 nt. The internal region displays a Primer Binding Site (PBS) complementary to a tRNASer, three Open Reading Frames (ORFs) for gag, pol, and env genes, and a Polypurine Tract (PPT) adjacent to the 3´LTR (Friesen and Nissen 1990;Lerch and Friesen 1992; Hajek and Friesen 1998).
Structure
Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:
| MA=matrix
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PR=protease
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DU or DUT=dUTPase
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TM=transmembrane
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TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
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| CA=capsid
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RT=reverse transcriptase
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INT=Integrase
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CHR=chromodomain
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| NC=nucleocapsid
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RH=RNaseH
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SU=surface
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MOV=movement protein
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| PPT=polypurine tract
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PBS=primer binding site
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ATF=aphid transmission factor
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VAP=virion associated protein
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Related literature
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