Element:LPDV

Revision as of 08:00, 3 May 2010 by imported>Ldominguez
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Description

Lymphoproliferative Disease Virus (LPDV) is a retrovirus that induces an acute, horizontally transmitted turkey disease that is often fatal (Gazit et al. 1979; Yaniv et al. 1979). LPDV represents a distinct group of avian retroviruses closely related to avian sarcoma-leukemia viruses (Chajut et al. 1992). The genomic structure of LPDV is 7.1 Kb in size including pro-LTRs of 118 and 257 nt. The internal region of this retrovirus displays a Primer Binding Site (PBS) complementary to a tRNATrp, Open Reading Frames (ORFs) for gag, pro, pol, and env genes characteristic of retroviruses, four small ORFs whose function is unclear, and a Polypurine Tract (PPT) adjacent to the 3´LTR (Gak et al. 1991; Sarid et al. 1994).

Structure

Lpdv.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession: U09568
Clade: Undetermined
Cluster or genus: Alpharetrovirus
Branch or class: Class 2
Family: Retroviridae
System: LTR retroelements
Host:
Explore the Tree Life Project
Meleagris gallopavo.gif
Meleagris gallopavo
Image, courtesy of Cal Vornberger
Browse all elements



Welcome to the Gypsy Database (GyDB) an open editable database about the evolutionary relationship of viruses, mobile genetic elements (MGEs) and the genomic repeats where we invite all authors to contribute with their knowledge to improve and expand the topics.
Cite this project:

Llorens, C., Futami, R., Covelli, L., Dominguez-Escriba, L., Viu, J.M., Tamarit, D., Aguilar-Rodriguez, J. Vicente-Ripolles, M., Fuster, G., Bernet, G.P., Maumus, F., Munoz-Pomer, A., Sempere, J.M., LaTorre, A., Moya, A. (2011) The Gypsy Database (GyDB) of Mobile Genetic Elements: Release 2.0 Nucleic Acids Research (NARESE) 39 (suppl 1): D70-D74 doi: 10.1093/nar/gkq1061

Contact - Announcements - Acknowledgments - Terms of use and policy - Help - Donate
Donating legal disclaimer - Terms and conditions of the donation