From The Gypsy Database


Tto1, a Ty1/Copia-like LTR retrotransposon described in Nicotiana tabacum (Hirochika et al. 1996). This element belongs to the Tork clade within Branch 2 of the Ty1/Copia family (Llorens et al. 2009). Its genome is 5300 bp in size, including two identical LTRs of 574 bp long. The LTRs flanked internal region encodes for a single Open Reading Frame (ORF) of 1338 amino acids with the typical gag and pol structure: gag, protease, integrase, reverse transcriptase and ribonuclease H (Hirochika et al. 1996).



Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession:1167522
Cluster or genus:Undetermined
Branch or class:Branch 2
System:LTR retroelements
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Nicotiana tabacum.jpg
Nicotiana tabacum
Courtesy of the New York Botanical Garden
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