Element:RCHO-K1

From The Gypsy Database

Description

Chinese Hamster Ovary retrovirus (RCHO) is a C-type retrovirus that in integrating recognizes a target G-repeat sequence belonging to the short interspersed element family of retroposons. This retrovirus has been detected in CHO-K1 cells and in Chinese hamster liver (Lie et al. 1994). The genomic structure of RCHO-K1 is 9.6 Kb size including LTRs 465 and 456 nt. The internal region of this retrovirus displays a Primer Binding Site (PBS) complementary to a tRNAPro, two Open Reading Frames (ORFs) gag-pro and pol (pol displays three frameshiftings), an ORF for env gene, and also a Polypurine Tract (PPT) adjacent to the 3´LTR (Lie et al. 1994).

Structure

Rcho-k1.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession:U09104
Clade:Undetermined
Cluster or genus:Gammaretrovirus
Branch or class:Class 1
Family:Retroviridae
System:LTR retroelements
Host:
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