Element:Mdg3

From The Gypsy Database

Description

Mdg3 is a LTR retrotransposon described in the genome of Drosophila melanogaster (Ilyin et al. 1985). Mdg3 belongs, along with other Ty3/Gypsy LTR retrotransposons, to Micropia/mdg3 clade (Malik and Eickbush 1999). The genomic structure of mdg3 is 5.5Kb in size including LTRs with a size oscillating between 267 and 293 nt (depending on the mdg3 variant). The internal region of this element displays a Primer Binding Site (PBS), a single Open Reading Frame (ORF) that codifies for a gag-pol polyprotein, and a Polypurine Tract (PPT) adjacent to the 3´LTR (Ilyin et al. 1985; Dzhumgaliev et al. 1986; Avedisov and Il'in,Iu. 1995).

Structure

Mdg3.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession:X95908
Clade:Micropia/Mdg3
Cluster or genus:Undetermined
Branch or class:Branch 2
Family:Ty3/Gypsy
System:LTR retroelements
Host:
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Drosophila melanogaster.gif
Drosophila melanogaster
Image, courtesy of Andreas Trepte, Max-Planck Institute for Molecular Genetics
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