From The Gypsy Database


CoDi4.5 is a Ty1/Copia LTR retrotransposon described in the genome of the marine algae phytoplankton Thalassiosira pseudonana (Maumus et al. 2009; Bowler et al. 2008). This element belongs to CoDi-I clade, within Branch 1 of the Ty1/Copia family (Llorens et al. 2009). Interestingly, CoDi-I represents the first described set of Ty1/Copia elements carrying a putative chromodomain at the C-terminus of the pol-INT domain (Llorens et al. 2009) similarly to Ty3/Gypsy chromoviruses (Marin and Lloréns 2000), which use this feature for chromatin integration (Gao et al. 2008).

CoDi4.5 genome, of 6715 bp in size, includes 235-bp LTRs that flank a long Open Reading Frame (ORF), interrupted by one stop codon, displaying the gag and pol typical structure of the Ty1/Copia LTR retrotransposons (gag, protease, integrase, reverse transcriptase and ribonuclease H, for more details, see Maumus et al. 2009).



Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession:169639616
Cluster or genus:Undetermined
Branch or class:Branch 1
System:LTR retroelements
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Thalassiosira pseudonana.jpg
Thalassiosira pseudonana
Courtesy of Nils Kröger, Georgia Institute of Technology, Atlanta, USA
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