Element:CFG1

From The Gypsy Database

Description

CFG1 is a Ty3/Gypsy LTR retrotransposon described in the genome of the mollusca Chlamys Farreri ( Wang et al 2007). Expression of CFG1 appears to be controlled by a post-transcriptional gene silencing mechanisms associated to reverse transcriptase (RT) methylation ( Wang et al 2007). CFG1 belongs, along with other LTR retrotransposons, to Mag a large Ty3/Gypsy cluster widely distributed in both protostomes and deuterostomes (for more details, see Malik and Eickbush 1999; Volff et al. 2001; Tubio, Naveira and Costas 2004). The genomic structure of CFG1 is 4.7 Kb in size including LTRs of 192 and 189 nt. The internal region of this element displays a Primer Binding Site (PBS), a single Open Reading Frame (ORF) that codes for a single gag-pol polyprotein, and a Polypurine Tract (PPT) adjacent to the 3´LTR ( Wang et al 2007).

Structure

CGF-1.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Mobile DNA II. (Craig et al. 2002)

Genbank accession:124055237
Clade:A-clade
Cluster or genus:Mag
Branch or class:Branch 2
Family:Ty3/Gypsy
System:LTR retroelements
Host:
Explore the Tree Life Project
Chlamys farresi.jpg
Chlamys farresi
Courtesy of José Liétor Gallego
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