Element:BAEVM

From The Gypsy Database

Description

Baboon Endogenous Virus (BaEVM) is a C-type endogenous retrovirus that occurs in Old World apes. BAEVM was originally isolated in mandrill cellular cultures (Beneviste et al. 1974; Todaro et al. 1974) and is detectable in placental tissue (Todaro, Sherr and Beneviste 1976). The genome of BaEVM strain M7 is taken as a representative. The genomic structure of this retrovirus is 8.5 Kb size including LTRs of 0.55 Kb, its internal region displays a Primer Binding Site (PBS) complementary to a tRNAPro, three Open Reading Frames (ORFs) for gag, pol and env genes characteristic of retroviruses; and a Polypurine Tract (PPT) adjacent to the 3′LTR ( Kato et al. 1987).

Structure

Baevm.png


Figure not to scale. If present, long terminal repeats (LTRs) have been highlighted in blue. Amino acid motifs noted with lines indicate the conserved residues in each protein domain, abbreviations below mean:

MA=matrix PR=protease DU or DUT=dUTPase TM=transmembrane TAV or IBMP=transactivator/viroplasmin or inclusion body matrix protein
CA=capsid RT=reverse transcriptase INT=Integrase CHR=chromodomain
NC=nucleocapsid RH=RNaseH SU=surface MOV=movement protein
PPT=polypurine tract PBS=primer binding site ATF=aphid transmission factor VAP=virion associated protein

Related literature

Genbank accession:D10032
Clade:Undetermined
Cluster or genus:Gammaretrovirus
Branch or class:Class 1
Family:Retroviridae
System:LTR retroelements
Host:
Explore the Tree Life Project
Mandrill sp.gif
Mandrill sp.
Image, Joaquin Panadero,
Copyright, GyDB, Biotech Vana
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